Novel antimicrobial polymer films active against bacteria and fungi
Novel antimicrobial polymer films active against bacteria and fungi
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DOI：
10.1002/pc.22410
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发表时间：
2013-09-01
影响因子：
5.2
通讯作者：
Incarnato, Loredana
中科院分区：
文献类型：
--
作者：
Piotto, Stefano;Concilio, Simona;Incarnato, Loredana
我们报告的合成和表征的偶氮苯为基础的化合物。该分子显示出对金黄色葡萄球菌和白色念珠菌的高抗微生物活性，如通过溶液中的体外微生物测试所证明的。将该抗微生物分子引入两种聚烯烃基质中实现了两种抗微生物聚合物体系。将含有不同百分比的偶氮化合物的聚合物材料模铸，并对所得膜进行体外抗相同革兰氏阳性细菌和真菌的测试。该膜在低偶氮染料百分比（高达0.01%）下显示出杀生物活性，通过简单的熔融加工为制造抗菌聚合物膜提供了希望。(c)2013年塑料工程师学会
We report on the synthesis and the characterization of an azobenzene-based compound. The molecule shows high antimicrobial activity against Staphilococcus aureus and Candida albicans, as demonstrated by in vitro microbiological test in solution. Two antimicrobial polymeric systems were realized introducing this antimicrobial molecule in two polyolefin matrices. The polymeric materials containing different percentages of azo-compound were mold-casted and the obtained films were tested in vitro against the same Gram-positive bacterium and fungus. The films show biocide activity at low percentage of azo dye (up to 0.01%), holding promise for the fabrication of bacteria-resistant polymer films by means of simple melt processing. (c) 2013 Society of Plastics Engineers