Mercuric triflate-catalyzed tandem cyclization leading to polycarbocycles
Mercuric triflate-catalyzed tandem cyclization leading to polycarbocycles
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DOI：
10.1021/ol047472t
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发表时间：
2005-02-03
期刊：
影响因子：
5.2
通讯作者：
Nishizawa, M
中科院分区：
文献类型：
--
作者：
Imagawa, H;Iyenaga, T;Nishizawa, M
We developed Hg(OTf)(2)-catalyzed cyclization of (E)-1,3-dimethoxy-5-(4-methyl-3-nonen-7-ynyl)benzene leading to the formation of (4aS*,10aS*)-3,4,4a,9,10,10a-hexahydro-5,7-dimethoxy-1,4a-dimethylphenanthrene in 98% yield with up to 100 catalytic turnovers. This is the first mercuric salt-catalyzed biomimetic tandem cyclization.
