High perceived stress in patients on opioid agonist therapies during rapid transitional response to the COVID-19 pandemic in Ukraine.
High perceived stress in patients on opioid agonist therapies during rapid transitional response to the COVID-19 pandemic in Ukraine.
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DOI：
10.3389/fpubh.2023.1231581
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发表时间：
2023
影响因子：
5.2
通讯作者：
Madden, Lynn M.
中科院分区：
文献类型：
--
作者：
Galvez, Samy J.;Altice, Frederick L.;Meteliuk, Anna;Ivasiy, Roman;Machavariani, Eteri;Farnum, Scott O.;Fomenko, Tetiana;Islam, Zahedul;Madden, Lynn M.
2019冠状病毒病大流行导致乌克兰的医疗服务明显中断，这与治疗阿片类药物使用障碍（OUD）的紧急指导有关。OUD患者（一组具有高水平共病医学和精神疾病的患者）和处方阿片类激动剂治疗（OAT）的患者，如果被认为临床稳定，则迅速转为带回家给药。然而，这些变化对大流行期间患者压力和相关物质使用的影响尚不清楚。于二零二零年五月初，我们对乌克兰269名随机挑选的OAT患者进行了调查，以使用经验证的感知压力量表评估他们的压力水平和物质使用情况，并检查了严重感知压力的相关性。总计195（72.5%）符合中度至重度压力水平的标准，这与过去12个月内开始OAT独立相关（aOR：1.33; 95%CI：1.15-1.55），居住在大都市区（aOR：1.31; 95%CI：1.18-1.46），曾被他人要求分享其药物（aOR：1.13; 95%CI：1.02-1.25），并且到达治疗的运输时间增加超过10 min（aOR：1.16; 95%CI：1.04-1.29）。27例（10%）患者感觉复发的风险很高，而24例（8.9%）患者报告购买药物。在COVID-19疫情紧急指导后不久的一段非常不确定的时期，据报道，人们感受到的压力非常高。为了响应紧急指导，应筛查OAT患者的感知压力，并针对某些亚组提供额外的心理社会支持。
The COVID-19 pandemic resulted in marked disruptions in healthcare delivery in Ukraine related to emergency guidance in response to treating opioid use disorder (OUD). Patients with OUD, a group with high levels of comorbid medical and psychiatric disorders, and prescribed opioid agonist therapies (OAT) were rapidly shifted to take-home dosing if they were deemed clinically stable. The impact of these shifts on patient stress and related substance use during the pandemic, however, is unknown. In early May 2020, 269 randomly selected OAT patients in Ukraine were surveyed to assess their stress level and substance use using the validated Perceived Stress Scale and examined correlates of severe perceived stress. Overall, 195 (72.5%) met criteria for moderate to severe levels of stress, which was independently correlated with having started OAT within the past 12 months (aOR: 1.33; 95%CI: 1.15–1.55), living in a large metropolitan area (aOR: 1.31; 95%CI: 1.18–1.46), having been asked by others to share their medication (aOR: 1.13; 95%CI: 1.02–1.25), and having an increase of over 10 min in transportation time to get to treatment (aOR: 1.16; 95%CI: 1.04–1.29). Twenty seven (10%) patients felt at high risk of relapse, while 24 (8.9%) patients reported purchasing drugs. During a time of great uncertainty soon after emergency guidance to the COVID-19 pandemic, there was extraordinary high levels of perceived stress reported. In response to emergency guidance, OAT patients should be screened for perceived stress and certain subgroups should be targeted for additional psychosocial support.
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DOI：
10.3109/09687637.2015.1016397
发表时间：
2015
期刊：
Drugs (Abingdon, England)
影响因子：
--
作者：
Bojko MJ;Mazhnaya A;Makarenko I;Marcus R;Dvoriak S;Islam Z;Altice FL
通讯作者：
Altice FL
影响因子：
50
作者：
Altice, Frederick L.;Bromberg, Daniel J.;Dvoriak, Sergii;Meteliuk, Anna;Pykalo, Iryna;Islam, Zahedul;Azbel, Lyu;Madden, Lynn M.
通讯作者：
Madden, Lynn M.
影响因子：
1.5
作者：
Bjerge, Bagga;Nielsen, Bjarke
通讯作者：
Nielsen, Bjarke
影响因子：
2.5
作者：
Carroll, Jennifer J.
通讯作者：
Carroll, Jennifer J.
影响因子：
4.4
作者：
Bruce, R. Douglas;Dvoryak, Sergey;Altice, Frederick L.
通讯作者：
Altice, Frederick L.