Association between health literacy and HIV treatment adherence: further evidence from objectively measured medication adherence.
Association between health literacy and HIV treatment adherence: further evidence from objectively measured medication adherence.
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DOI：
10.1177/1545109708328130
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发表时间：
2008-11
期刊：
影响因子：
--
通讯作者：
Kalichman MO
中科院分区：
文献类型：
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作者：
Kalichman SC;Pope H;White D;Cherry C;Amaral CM;Swetzes C;Flanagan J;Kalichman MO
健康素养较低的人很容易出现健康问题。检验识字率和药物依从性之间关系的研究依赖于自我报告的依从性，这容易出现记忆错误，对于识字率差的人来说可能更是如此。研究健康素养与客观评估的艾滋病毒治疗依从性之间的关系。接受抗逆转录病毒治疗的男性和女性 (N = 145) 完成了健康素养测试和常见依从性标记的测量。通过未公布的药丸计数来监测药物依从性。中位依从率为 71%；与健康素养较高的个体相比，健康素养较低的参与者也表现出较差的依从性。分层回归显示，识字率比所有其他因素更能预测依从性。敏感性测试显示 80% 和 90% 依从性的结果相同。识字率和依从性之间的关联似乎很牢固，并通过药物依从性的客观测量得到证实。
People with lower health literacy are vulnerable to health problems. Studies that have examined the association between literacy and medication adherence have relied on self-reported adherence, which is subject to memory errors, perhaps even more so in people with poor literacy. To examine the association between health literacy and objectively assessed HIV treatment adherence. Men and women (N = 145) receiving antiretroviral therapies completed a test of health literacy and measures of common adherence markers. Medication adherence was monitored by unannounced pill counts. Median adherence was 71%; Participants with lower health literacy also demonstrated poorer adherence compared to individuals with higher literacy. Hierarchical regression showed literacy predicted adherence over and above all other factors. Sensitivity tests showed the same results for 80% and 90% adherence. The association between literacy and adherence appears robust and was confirmed using an objective measure of medication adherence.