Knowledge is power: general practitioners prescribing of new oral anticoagulants in Ireland.
Knowledge is power: general practitioners prescribing of new oral anticoagulants in Ireland.
复制标题
DOI：
10.1186/s13104-018-3597-x
复制
发表时间：
2018-07-16
影响因子：
1.8
通讯作者：
Bradley, C
中科院分区：
文献类型：
--
作者：
Murphy, A;Kirby, A;Bradley, C
目的：新型口服抗凝剂(NOAC)旨在克服华法林的缺点，但其药代动力学特性使处方复杂。因此，全科医生(全科医生)必须了解具体的治疗方法，以便最大限度地提高其益处，最大限度地减少其缺陷。这项研究探讨了爱尔兰全科医生对开NOAC的态度和经验，尽管爱尔兰明确的国家处方指南主张将华法林作为一线治疗，但首次开NOAC的患者数量正在增长。结果：使用从爱尔兰全科医生收集的原始数据，使用概率模型确定了影响全科医生开始开NOAC处方的可能性的因素。结果表明，46%的样本发起了NOAC处方，而全科医生的执业规模是影响这一比例的重要因素。分析表明，在全科医生开新药时被认为重要的信息来源方面没有差异。然而，在开始和非开始使用NOAC处方时，哪些因素被认为是重要的，这一点是不同的。这项研究的结果表明，更好地利用现有的信息和教育工具，为全科医生开出NOAC处方和管理NOAC患者是当务之急，以确保在正确的时间为正确的患者开出正确的抗凝剂。
OBJECTIVE: New oral anticoagulants (NOACs) aim to overcome warfarin's shortcomings, however their pharmacokinetic characteristics make prescribing complex. Thus it is imperative that general practitioners (GPs) are aware of specific treatments so as to maximise their benefits and minimise their pitfalls. This study explores GPs attitudes and experiences with prescribing NOACs in Ireland where, despite clear national prescribing guidelines advocating warfarin as first line therapy, the number of patients being prescribed NOACs for the first time is growing.RESULTS: Using primary data collected from GPs in Ireland the factors influencing the likelihood of a GP initiating a prescription for a NOAC are determined using a probit model. Results indicate 46% of the sample initiated NOAC prescriptions and GP practice size is a significant factor influencing this. Analysis revealed no difference regarding the sources of information considered important amongst GPs when prescribing new drugs. However, there were differences in which factors were considered important when prescribing anticoagulants between initiating and non-initiating NOAC prescribers. The results of this study suggest better utilisation of existing information and education tools for GPs prescribing NOACs and managing NOAC patients is imperative, to ensure the right anticoagulant is prescribed for the right patient at the right time.