Parotid gland lesions: separate and combined diagnostic value of conventional MRI, diffusion-weighted imaging and dynamic contrast-enhanced MRI
Parotid gland lesions: separate and combined diagnostic value of conventional MRI, diffusion-weighted imaging and dynamic contrast-enhanced MRI
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腮腺病变：常规MRI、弥散加权成像和动态增强MRI的单独和联合诊断价值
DOI：
10.1259/bjr.20150912
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发表时间：
2016-01-01
影响因子：
2.6
通讯作者：
Tao, Xiaofeng
中科院分区：
文献类型：
--
作者：
Yuan, Ying;Tang, Weiqing;Tao, Xiaofeng
目的：评价常规MRI、弥散加权成像（DWI）和动态增强MRI（DCE）鉴别腮腺良恶性病变的能力。方法：回顾性分析2010年1月至2014年12月间经病理证实的腮腺病变患者的MRI表现。比较两组患者的MRI形态学特征和表观弥散系数（ADC）、时间-信号强度曲线（TIC）等功能学特征。对于每处病变，分别计算单独常规MRI、常规MRI + DWI和/或+DCE-MRI的总分。进行统计分析，以评估这些特征和总评分与malignancy.Results：共207例患者（111男，96女，年龄：48.4 +/- 17.0岁），包括156良性和51恶性肿瘤。校正年龄、性别、吸烟、饮酒和肿瘤大小后，边缘不清、邻近组织浸润、颈部淋巴结肿大、ADC值
Objective: To evaluate the ability of conventional MRI, diffusion-weighted imaging (DWI) and dynamic contrast-enhanced (DCE) MRI to differentiate malignant and benign parotid lesions.Methods: A retrospective review of MRI findings was performed in patients with pathologically confirmed parotid lesions between January 2010 and December 2014. Morphological MRI characteristics and functional characteristics such as apparent diffusion coefficient (ADC) and pattern of time-signal intensity curve (TIC) were recorded and compared. For each lesion, summed scores were respectively calculated for conventional MRI alone, conventional MRI with DWI and/or with DCE-MRI. Statistical analyses were performed to assess the association of these characteristics and summed scores with malignancy.Results: A total of 207 patients (111 males and 96 females; age: 48.4 +/- 17.0 years) were included, consisting of 156 benign and 51 malignant tumours. After adjusting for age, sex, smoking status, alcohol use and tumour size, the lesions with ill-defined margin, adjacent tissue infiltration, cervical lymphadenopathy, ADC