Neuromodulation therapy for atrial fibrillation.
Neuromodulation therapy for atrial fibrillation.
复制标题
房颤的神经调节治疗。
DOI:
10.1016/j.hrthm.2022.08.011
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发表时间:
2023-01
期刊:
影响因子:
5.5
通讯作者:
Piccini, Jonathan P.
中科院分区:
文献类型:
--
作者:
Karatela, Maham F.;Fudim, Marat;Mathew, Joseph P.;Piccini, Jonathan P.
Atrial fibrillation has a multifactorial pathophysiology influenced by cardiac autonomic innervation. Both sympathetic and parasympathetic influences are pro-fibrillatory. Innovative therapies targeting the neurocardiac axis include catheter ablation or pharmacologic suppression of ganglionated plexi, renal sympathetic denervation, low-level vagal stimulation, and stellate ganglion blockade. To date, these therapies have variable efficacy. As our understanding of atrial fibrillation and the cardiac nervous system expands, our approach to therapeutic neuromodulation will continue evolving for the benefit of those with AF.
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