STRUCTURE AND EVOLUTION OF RIBOSOMAL AND 5-S DNAS IN XENOPUS-LAEVIS AND XENOPUS-MULLERI
STRUCTURE AND EVOLUTION OF RIBOSOMAL AND 5-S DNAS IN XENOPUS-LAEVIS AND XENOPUS-MULLERI
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DOI：
10.1101/sqb.1974.038.01.054
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发表时间：
1973-01-01
期刊：
影响因子：
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通讯作者：
SUGIMOTO, K
中科院分区：
文献类型：
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作者：
BROWN, DD;SUGIMOTO, K
已知结构的基因的分离提供了关于它们的排列和进化的信息。这种分析对于核糖体RNA的基因是最先进的，因为这些RNA可以容易地纯化用于基因的杂交测定。此外，这些基因在基因组中以许多拷贝存在，并且具有促进其纯化的不寻常的物理和化学特性（Wallace和Birnstiel，1966; Brown和Weber，1968 a）。编码18 S和28 S核糖体RNA（rDNA）结构的基因（Birnstiel等人，1966; Brown和Dawid，1968; Brown等人，1972）和低分子量5S核糖体RNA（5S DNA）的那些（Brown等，1971; Brown和Sugimoto，1973）已经从所述化合物中纯化出。
The isolation of genes of known structure has provided information on their arrangement and evolution. This analysis is most advanced for the genes for ribosomal RNAs due to the ease with which these RNAs can be purified for use in hybridization assays of the genes. In addition, the genes are present in many copies in the genome and have unusual physical and chemical characteristics that have facilitated their purification (Wallace and Birnstiel, 1966; Brown and Weber, 1968a). The genes coding for the structure of the 18 S and 28 S ribosomal RNAs (rDNA)(Birnstiel et al., 1966; Brown and Dawid, 1968; Brown et al., 1972) and those for the low molecular weight 5 S ribosomal RNA (5 S DNA)(Brown et al., 1971; Brown and Sugimoto, 1973) have been purified from the