Enhancing retention of an Internet-based cohort study of men who have sex with men (MSM) via text messaging: randomized controlled trial.

Enhancing retention of an Internet-based cohort study of men who have sex with men (MSM) via text messaging: randomized controlled trial.
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DOI:
10.2196/jmir.2756
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发表时间:
2013-08-27
影响因子:
7.4
通讯作者:
Sullivan PS
Sullivan PS
中科院分区:
医学2区
文献类型:
--
作者:
Khosropour CM;Johnson BA;Ricca AV;Sullivan PS

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在美国,与男性发生性关系的黑人和西班牙裔男性(MSM)受到艾滋病毒的影响不成比例。互联网是一个很有前途的工具,提供艾滋病毒预防干预措施,这些人,但保留的男男性接触者的颜色在纵向基于互联网的研究一直存在问题。短信随访可能会提高这些研究中的保留。在一项为期12个月的基于互联网的前瞻性研究中,对HIV阴性男男性接触者进行了一项为期12个月的前瞻性研究,该研究随机接受两个月一次的随访调查,无论是通过互联网浏览器在线还是通过短信。使用互联网的男男性行为者是通过社交网络和互联网约会网站上的横幅广告招募的。年龄≥18岁的白色、黑人和西班牙裔男性,完成在线基线调查,并返回家中HIV检测试剂盒,检测结果为HIV阴性,符合条件。男性被随机分配接受随访调查,每2个月在互联网上或通过短信12个月(非盲)。我们使用至事件发生时间方法比较了2个随访组的失访率(定义为多次系统性联系尝试后对随访调查无应答),包括总体和人种/种族。结果报告为随机接受短信随访与在线随访相比的男性失访率的风险比(HR)和95%置信区间(CI)。在开始在线基线调查的1489名合格和同意的男性中,895人(60%)完成了调查,并收到了一个家庭艾滋病毒检测试剂盒。其中,895人中的710人(79%)返回了家中的HIV检测试剂盒,检测HIV阴性,并进行了前瞻性随访。研究队列包括66%的白色男性(470/710)、15%的黑人男性(106/710)和19%的西班牙裔男性(134/710)。在12个月时,77%(282/366)的随机在线随访男性保留在研究中,而70%(241/344)的随机短信随访男性保留在研究中(HR=1.30,95% CI 0.97-1.73)。对于两个白色受试者,短信组的失访率均非显著高于在线组。(HR=1.43,95% CI 0.97-1.73)和西班牙裔男性(HR=1.71,95% CI 0.91-3.23);但是,在此情况下,与在线随访相比,接受短信随访的黑人男性的失访率并不显着降低(HR=0.78,95% CI 0.41-1.50)。在线组中,黑人男性失访的可能性显著高于白色男性(HR=2.25,95% CI 1.36-3.71),但短信组的情况并非如此(HR=1.23,95% CI 0.70-2.16)。我们保留了超过70%的MSM参加了12个月的在线研究;因此,让男性参加在线研究有足够的时间来评估持续的结果是可能的。短信跟进的在线队列的男男性接触者是可行的,并可能导致更高的保留黑人男男性接触者。
Black and Hispanic men who have sex with men (MSM) are disproportionately affected by HIV in the United States. The Internet is a promising vehicle for delivery of HIV prevention interventions to these men, but retention of MSM of color in longitudinal Internet-based studies has been problematic. Text message follow-up may enhance retention in these studies. To compare retention in a 12-month prospective Internet-based study of HIV-negative MSM randomized to receive bimonthly follow-up surveys either through an Internet browser online or through text messages. Internet-using MSM were recruited through banner advertisements on social networking and Internet-dating sites. White, black, and Hispanic men who were ≥18, completed an online baseline survey, and returned an at-home HIV test kit, which tested HIV negative, were eligible. Men were randomized to receive follow-up surveys every 2 months on the Internet or by text message for 12 months (unblinded). We used time-to-event methods to compare the rate of loss-to-follow-up (defined as non-response to a follow-up survey after multiple systematically-delivered contact attempts) in the 2 follow-up groups, overall and by race/ethnicity. Results are reported as hazard ratios (HR) and 95% confidence intervals (CI) of the rate of loss-to-follow-up for men randomized to text message follow-up compared to online follow-up. Of 1489 eligible and consenting men who started the online baseline survey, 895 (60%) completed the survey and were sent an at-home HIV test kit. Of these, 710 of the 895 (79%) returned the at-home HIV test kit, tested HIV-negative, and were followed prospectively. The study cohort comprised 66% white men (470/710), 15% (106/710) black men, and 19% (134/710) Hispanic men. At 12 months, 77% (282/366) of men randomized to online follow-up were retained in the study, compared to 70% (241/344) men randomized to text message follow-up (HR=1.30, 95% CI 0.97-1.73). The rate of loss-to-follow-up was non-significantly higher in the text message arm compared to the online arm for both white (HR=1.43, 95% CI 0.97-1.73) and Hispanic men (HR=1.71, 95% CI 0.91-3.23); however, loss-to-follow-up among black men was non-significantly lower among those who received text message follow-up compared to online follow-up (HR=0.78, 95% CI 0.41-1.50). In the online arm, black men were significantly more likely to be lost to follow-up compared to white men (HR=2.25, 95% CI 1.36-3.71), but this was not the case in the text message arm (HR=1.23, 95% CI 0.70-2.16). We retained >70% of MSM enrolled in an online study for 12 months; thus, engaging men in online studies for a sufficient time to assess sustained outcomes is possible. Text message follow-up of an online cohort of MSM is feasible, and may result in higher retention among black MSM.
DOI: 10.2196/jmir.1797
发表时间: 2011-04-01
影响因子: 7.4
作者:
Sullivan, Patrick S.;Khosropour, Christine M.;DiClemente, Ralph J.
通讯作者: DiClemente, Ralph J.
DOI: 10.1080/09540120902730013
发表时间: 2009-01-01
影响因子: 1.7
作者:
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DOI: 10.1089/apc.2012.0355
发表时间: 2013-02-01
影响因子: 4.9
作者:
Calabrese, Sarah K.;Rosenberger, Joshua G.;Reece, Michael
通讯作者: Reece, Michael
MSM 艾滋病毒预防的新兴技术:我们的经验和前进的方向。
DOI: 10.1097/qai.0b013e3182949e85
发表时间: 2013-06-01
期刊: Journal of acquired immune deficiency syndromes (1999)
影响因子: --
作者:
Sullivan PS;Grey JA;Simon Rosser BR
通讯作者: Simon Rosser BR
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影响因子: 1.7
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