Diurnal variability of lung function and its association with sleep among patients with asthma
Diurnal variability of lung function and its association with sleep among patients with asthma
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DOI：
10.1080/02770900701645686
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发表时间：
2007-01-01
影响因子：
1.9
通讯作者：
Krouse, John H.
中科院分区：
文献类型：
--
作者：
Krouse, Helene J.;Krouse, John H.
本前瞻性探索性研究探讨了20名成人哮喘患者肺功能的昼夜变化及其与睡眠和生活质量（QOL）的关系。在睡前和醒来时评估7天的呼气峰流速（PEF）。PEF变异性与QOL无相关性。13项多导睡眠图测量中有6项与夜间PEF下降显著相关。下降幅度最大的人需要更长的时间才能入睡并进入第一阶段睡眠，睡眠时间更短，睡眠效率更差。PEF的昼夜变化反映了不良的睡眠质量，但对QOL的影响往往是不被注意的。
This prospective exploratory story examined diurnal variations in pulmonary function and their association with sleep and quality of life (QOL) in 20 adult asthmatics. Peak expiratory flow (PEF) was assessed for 7 days, before bedtime and upon awakening. There was no association between PEF variability and QOL. Six of 13 polysomnographic measures were significantly correlated with overnight decline in PEF. Individuals with greatest decline took longer to fall asleep and enter Stage 1 sleep, spent less time asleep, and experienced poorer sleep efficiency. Diurnal variations in PEF reflect adverse sleep quality, yet impact on QOL is often unnoticed.