Applications of automation in cervical cancer screening.
Applications of automation in cervical cancer screening.
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DOI：
10.1097/00128360-199801000-00005
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发表时间：
1998-01-01
影响因子：
3.7
通讯作者：
Jones, H W 3rd
中科院分区：
文献类型：
--
作者：
Doornewaard, H;van den Tweel, J G;Jones, H W 3rd
为了提高宫颈巴氏涂片(Pap)的灵敏度，目前已有几种自动化设备上市。在过去的两年里，美国食品和药物管理局批准了其中三个设备，每个设备的操作方式都不同于其他设备。ThinPrep 2000是一种用液体涂片收集技术取代传统巴氏涂片的方法，该技术允许制备薄层，解决了传统涂片上模糊血液、炎症和细胞重叠的问题。AutoPap 300 QC是一种重新筛选设备，可以从一批底片涂片中选择10%最有可能的异常涂片进行手动重新筛选。PAPNET检测系统是一种基于神经网络的半自动筛查系统，用于对阴性巴氏涂片进行辅助检测。该系统选择并显示看起来最异常的细胞，供细胞技术员检查，从而提高了对遗漏异常的检测。讨论了引入这些设备用于宫颈癌检测的有效性。
To increase the sensitivity of the cervical Papanicolaou (Pap) smear, several automated devices now are commercially available. In the last 2 years, the U.S. Food and Drug Administration approved three of these devices, each of which operates differently from the others. The ThinPrep 2000 is a method whereby the traditional Pap smear is substituted by a liquid-based smear collection technique that allows the preparation of thin layers, which addresses the problems of obscuring blood, inflammation, and overlapping cells on traditional smears. The AutoPap 300 QC is a rescreening device that selects from a batch of negative smears the 10% most likely abnormal smears for manual rescreening. The PAPNET Testing System is a neural network-based semiautomated screening system used for adjunctive testing of negative Pap smears. The system selects and displays the most abnormal-looking cells for review by the cytotechnologist, thus improving the detection of missed abnormalities. The effectiveness of the introduction of these devices for cervical cancer detection is discussed.