Polynuclear Aromatic Amines as N-Nucleophiles in the ipso-Substitution of the Cyano Group in 1,2,4-Triazines
Polynuclear Aromatic Amines as N-Nucleophiles in the ipso-Substitution of the Cyano Group in 1,2,4-Triazines
复制标题
DOI：
10.1134/s1070428020010268
复制
发表时间：
2020-04-24
影响因子：
0.900
通讯作者：
O. N. Chupakhin
中科院分区：
文献类型：
--
作者：
E. S. Starnovskaya;M. I. Savchuk;Ya. K. Shtaitz;D. S. Kopchuk;I. S. Kovalev;D. E. Pavlyuk;A. F. Khasanov;G. V. Zyryanov;O. N. Chupakhin
研究了在1,2,4-三嗪的5-氰基的异位取代中，多核芳香胺作为n -亲核试剂的可能性。证明了芳香胺的结构对反应结果的影响。以3-氨基联苯基为原料，得到相应的5-氨基- n -（联苯基-3-基）-1,2,4-三嗪，收率高达88%。
The possibility of use of polynuclear aromatic amines as N-nucleophiles in the ipso-substitution of the 5-cyano group in 1,2,4-triazines has been studied. The influence of the structure of the aromatic amine on the result of the reaction has been demonstrated. With 3-aminobiphenyls the corresponding 5-amino-N-(biphenyl-3-yl)-1,2,4-triaizines have been obtained with yields of up to 88%.