Different effects of phencyclidine and methamphetamine on firing activity of medial prefrontal cortex neurons in freely moving rats

Different effects of phencyclidine and methamphetamine on firing activity of medial prefrontal cortex neurons in freely moving rats
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DOI:
10.1016/s0006-8993(02)03967-7
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发表时间:
2003-02
期刊:
影响因子:
2.9
通讯作者:
E. Jodo;Yoshiaki Suzuki;S. Takeuchi;S. Niwa;Y. Kayama
E. Jodo;Yoshiaki Suzuki;S. Takeuchi;S. Niwa;Y. Kayama
中科院分区:
医学3区
文献类型:
--
作者:
E. Jodo;Yoshiaki Suzuki;S. Takeuchi;S. Niwa;Y. Kayama

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本研究的目的是比较系统管理MAP与苯环利定(PCP),这两种诱导可比的运动活动,对自由活动大鼠内侧前额叶皮层(mPFC)神经元放电活动的影响。结果表明,与PCP不同,急性给予MAP对mPFC神经元的放电活动几乎没有影响。
The purpose of this study was to compare the effects of systemically administered MAP with those of phencyclidine (PCP), both of which induced comparable locomotor activity, on firing activity of medial prefrontal cortex (mPFC) neurons in freely moving rats. The results show that, unlike PCP, acutely administered MAP produced little changes in firing activity of mPFC neurons.