None of polymorphism of ovine fecundity major genes FecB and FecX was tested in goat
None of polymorphism of ovine fecundity major genes FecB and FecX was tested in goat
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DOI：
10.1016/j.anireprosci.2007.08.013
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发表时间：
2008-11-01
影响因子：
2.2
通讯作者：
Yang, Li-Guo
中科院分区：
文献类型：
--
作者：
Hua, Guo-Hua;Chen, Shi-Lin;Yang, Li-Guo
采用强制PCR-RFLP方法，对波尔（209头）、海门（128头）、产羔数1.4~2.7个山羊群或品种的550只山羊的BMPR-IB基因（FecB）突变Q249R和BMP15基因位点FecX（1）、FecX（H）、FecX（G）、FecX（B）进行多态性分析。第二代波尔山羊与黄淮山羊（82）、黄淮（71）、努比（37）、马头（23）山羊杂交。在这些帕特品种及其杂交品种中没有检测到任何突变。这些结果表明山羊的繁殖力与绵羊的 BMPR-IB 和 BMP15 中的相同基因座无关。因此，有必要寻找其他基因或位点，以发展标记辅助选择技术并研究山羊的繁殖机制。 (C) 2007 Elsevier B.V. 保留所有权利。
The polymorphism of mutation Q249R in BMPR-IB gene (FecB) and loci FecX(1), FecX(H), FecX(G), FecX(B) in BMP15 gene was analyzed by forced PCR-RFLP method in 550 individuals from 6 flocks or breeds of goats with litter size varied from 1.4 to 2.7 including Boer (209), Haimen (128), second generation of Boer goat crossed with Huanghuai goat (82), Huanghuai (71), Nubi (37) and Matou (23) goat. None of mutations was detected in these Pat breeds and their crossbreed. These results suggest that fecundity of goat is not linked to the same loci in BMPR-IB and BMP15 as sheep. Therefore, it is necessary to seek for other genes or loci in order to develop marker assistance selection techniques and study the prolific mechanism of the goat. (C) 2007 Elsevier B.V. All rights reserved.