Acupuncture for irritable bowel syndrome: A blinded placebo-controlled trial
Acupuncture for irritable bowel syndrome: A blinded placebo-controlled trial
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DOI：
10.3748/wjg.v11.i26.4040
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发表时间：
2005-07-14
影响因子：
4.3
通讯作者：
Pitcher, Max
中科院分区：
文献类型：
--
作者：
Forbes, Alastair;Jackson, Sue;Pitcher, Max
目的：肠易激综合征（IBS）是一种常见的疾病，许多患者无法从常规治疗中找到足够的缓解症状。这项研究测试的索赔，针灸是有效的，大多数这些patients.METHODS：一个前瞻性的，盲目的，假针灸对照试验，中国传统针灸在欧洲的一个研究生教学医院进行。招募了60例确诊为IBS的患者。设盲的对照是由两名针灸师中的第二名进行的假针灸，这两名针灸师单独知道随机化，并且在其他方面遵循第一名的处方。主要终点是13周时症状评分的明确下降（通过意向治疗）。先前的预期是30%的安慰剂反应，70%的反应率从针灸，其中研究是充分powers.Results：患者在治疗组和假手术组改善显着在研究期间，平均改善分数是相等的（-1.9）和显着的（P
AIM: Irritable bowel syndrome (IBS) is a common disorder and many patients fail to find adequate relief from conventional therapies for their symptoms. This study tests the claim that acupuncture is effective for a majority of these patients.METHODS: A prospective, blinded, sham acupuncture-controlled trial of traditional Chinese acupuncture was performed at a single postgraduate teaching hospital in Europe. Sixty patients with well-established IBS were recruited. The blinded comparator was sham acupuncture administered by the second of two acupuncturists who alone was aware of the randomization, and who otherwise followed the prescription of the first. The primary end-point was a defined fall in the symptom score at 13 wk (by intention to treat). The prior expectation was a 30% placebo response, and a response rate of 70% from acupuncture, for which the study was adequately powered.RESULTS: Patients in treated and sham groups improved significantly during the study-mean improvement in scores being equal (minus 1.9) and significant for both (P