Practical synthesis of dirhodium(II) Tetrakis[N-phthaloyl-(S)-tert-leucinate]
Practical synthesis of dirhodium(II) Tetrakis[N-phthaloyl-(S)-tert-leucinate]
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DOI：
10.1248/cpb.53.1366
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发表时间：
2005-10-01
影响因子：
1.7
通讯作者：
Hashimoto, S
中科院分区：
文献类型：
--
作者：
Tsutsui, H;Abe, T;Hashimoto, S
报道了一种高效、可靠的四[N-邻苯二甲酰基-(S)-叔亮氨酸]-Rh-2(S-PtTl)(4)催化剂的制备方法。(S)-叔亮氨酸在玻色法中的N-邻苯二甲酰化反应基本上没有外消旋，是该反应的关键。
An efficient and reliable procedure for the preparation of dirhodium(II) tetrakis[N-phthaloyl-(S)-tert-leucinate], Rh-2(S-PTTL)(4), a universally effective catalyst for a range of enantioselective carbene transformations, is described. The N-phthaloylation of (S)-tert-leucine by the method of Bose with essentially no racemization is a key to this process.