PHYSICAL-FITNESS AND ALL-CAUSE MORTALITY IN HYPERTENSIVE MEN
PHYSICAL-FITNESS AND ALL-CAUSE MORTALITY IN HYPERTENSIVE MEN
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DOI：
10.3109/07853899109148065
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发表时间：
1991-08-01
影响因子：
4.4
通讯作者：
GIBBONS, LW
中科院分区：
文献类型：
--
作者：
BLAIR, SN;KOHL, HW;GIBBONS, LW
在不同身体健康水平的人群中，研究了血压正常和高血压男性的全因死亡率。受试者为10，224名健康血压正常的男性和1，832名报告有高血压病史但其他方面健康的男性。体能通过最大跑台运动试验确定。在1970-1981年期间进行了基线预防性医学检查，并在1985年对队列进行了死亡率监测。在血压正常的男性中有240例死亡，在高血压男性中有78例死亡。在血压正常的男性中，每10，000人年随访中的全因死亡率在最不健康的五分之一中为64.0，在最健康的五分之一中为18.6。高血压男性的相应患病率为110.5至24.8。根据基线静息收缩压（< 140 mmHg和大于或等于140 mmHg），将受试者进一步分为低血压组和高血压组。在两个测量的血压分层中，血压正常和高血压的男性健康状况较好，死亡率低于健康状况较差的男性。在调整年龄、血清胆固醇、静息收缩压、体重指数、当前吸烟习惯和随访时间的影响后，多元逻辑回归分析证实了健康状况与全因死亡率之间的关系。我们的结论是，低水平的身体素质会导致血压正常和高血压男性全因死亡的风险增加。
All-cause death rates in normotensive and hypertensive men were examined across physical fitness levels. Subjects were 10,224 healthy normotensive men and 1,832 men who reported a history of hypertension, but were otherwise healthy. Physical fitness was determined by maximal treadmill exercise testing. Baseline preventive medical examinations were given during 1970-1981, and mortality surveillance was conducted on the cohort through 1985. There were 240 deaths in the normotensive men and 78 deaths in hypertensive men. Age-adjusted all-cause mortality rates per 10,000 man-years of follow-up in normotensive men ranged from 64.0 in the least fit quintile to 18.6 in the most fit quintile. Corresponding rates for hypertensive men were 110.5 to 24.8. Subjects were further classified into lower and higher blood pressure groups by baseline resting systolic blood pressure (< 140 mmHg and greater-than-or-equal-to 140 mmHg). Normotensive and hypertensive men who were more fit had lower death rates compared to less fit men within both of the measured blood pressure strata. The relation between fitness and all-cause mortality held in multiple logistic regression analyses after adjustment for the influence of age, serum cholesterol, resting systolic blood pressure, body mass index, current smoking habit, and length of follow-up. We conclude that low levels of physical fitness result in an increased risk for all-cause mortality in normotensive and hypertensive men.