Similarity in the fatigue behavior of trabecular bone across site and species
Similarity in the fatigue behavior of trabecular bone across site and species
复制标题
DOI：
10.1016/s0021-9290(03)00245-8
复制
发表时间：
2004-02-01
影响因子：
2.4
通讯作者：
Keaveny, TM
中科院分区：
文献类型：
--
作者：
Haddock, SM;Yeh, OC;Keaveny, TM
在提高知识的背景下，骨小梁的结构功能关系的循环载荷，我们假设，S-N曲线的骨小梁的循环压缩载荷，在占单调强度行为的差异，不依赖于任何网站或物种。35个新鲜冷冻的老年人椎骨松质骨核心，从9个供体获得（平均值+/-S.D.，年龄= 74+/-17岁），在sigma/E-0值（施加应力与疲劳前弹性模量的比率）范围为0.0026至0.0070的压缩条件下进行生物力学测试，并与文献数据（J. Biomech. Eng.120（1998）647-654），用于年轻牛胫骨小梁骨（n = 37）。正如牛骨报告的那样，人椎骨的失效循环次数与σ/E-0呈幂律关系（r（2）= 0.54，n = 35）。这些数据与牛骨报告的数据的定量比较支持我们的假设。也就是说，当考虑到两种骨之间平均单调屈服应变的差异时，单一S-N曲线适用于合并数据（r（2）= 0.75，n = 72）。由于老年人脊椎骨和年轻牛胫骨骨小梁代表两种非常不同类型的骨小梁的体积分数和架构，这些研究结果表明，占主导地位的失败机制，在骨小梁循环载荷发生在超微结构水平。(C)2003 Elsevier Ltd.保留所有权利。
Within the context of improving knowledge of the structure function relations for trabecular bone for cyclic loading, we hypothesized that the S-N curve for cyclic compressive loading of trabecular bone, after accounting for differences in monotonic strength behavior, does not depend on either site or species. Thirty-five cores of fresh-frozen elderly human vertebral trabecular bone, harvested from nine donors (mean+/-S.D., age = 74+/-17 years), were biomechanically tested in compression at sigma/E-0 values (ratio of applied stress to pre-fatigue elastic modulus) ranging from 0.0026 to 0.0070, and compared against literature data (J. Biomech. Eng. 120 (1998) 647-654) for young bovine tibial trabecular bone (n = 37). As reported for the bovine bone, the number of cycles to failure for the human vertebral bone was related to sigma/E-0 by a power-law relation (r(2) = 0.54, n = 35). Quantitative comparison of these data against those reported for the bovine bone supported our hypothesis. Namely, when the differences in mean monotonic yield strain between the two types of bone were accounted for, a single S-N curve worked well for the pooled data (r(2) = 0.75, n = 72). Since elderly human vertebral and young bovine tibial trabecular bone represent two very different types of trabecular bone in terms of volume fraction and architecture, these findings suggest that the dominant failure mechanisms in trabecular bone for cyclic loading occur at the ultrastructural level. (C) 2003 Elsevier Ltd. All rights reserved.