B-MODE ULTRASOUND COMBINED WITH COLOR DOPPLER AND STRAIN ELASTOGRAPHY IN THE DIAGNOSIS OF NON-MASS BREAST LESIONS: A PROSPECTIVE STUDY
B-MODE ULTRASOUND COMBINED WITH COLOR DOPPLER AND STRAIN ELASTOGRAPHY IN THE DIAGNOSIS OF NON-MASS BREAST LESIONS: A PROSPECTIVE STUDY
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DOI：
10.1016/j.ultrasmedbio.2017.07.014
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发表时间：
2017-11-01
影响因子：
2.9
通讯作者：
Zni, Hui
中科院分区：
文献类型：
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作者：
Li, Lujing;Zhou, Xinchuan;Zni, Hui
超声 (US) 上显示的非肿块性乳腺病变是指没有相关肿块的区域。本研究的目的是评估将 B 型超声与彩色多普勒超声和应变弹性成像 (SE) 相结合是否可以改善超声对良性和恶性非肿块性乳腺病变的区分以及活检的决定。在这项前瞻性研究中，三位不同的放射科医生独立分析了 77 个非肿块性病变的 US 图像，并记录了四个数据集的乳腺成像报告和数据系统 (BI-RADS) 类别。另一位放射科医生分析了四个数据集的图像特征和 BI-RADS 类别。最终诊断是根据病理结果做出的。比较了数据集之间的受试者工作曲线下面积（AUC）、敏感性、特异性和准确性的值。 B 型超声联合彩色多普勒超声和 SE 的 AUC 大于单独使用 B 型超声的 AUC（0.666 与 0.828）（p = 0.011）。当 B 型超声与彩色多普勒和 SE 相结合时，活检决策的特异性从 6.5% 增加到 38.7%，而敏感性没有统计学上的显着变化 (p < 0.001)。彩色多普勒和SE的联合使用可以提高B超对非肿块性乳腺病灶良恶性的诊断价值以及对非肿块性乳腺病灶活检决策的特异性。 (C) 2017 年世界超声医学与生物学联合会。
Non-mass breast lesions on ultrasound (US) are areas without an associated mass. The purpose of this study was to evaluate whether combining B-mode US with color Doppler US and strain elastography (SE) improves US differentiation between benign and malignant non-mass breast lesions and the decision for biopsy. In this prospective study, three different radiologists analyzed the US images of 77 non-mass lesions independently and recorded Breast Imaging Reporting and Data System (BI-RADS) categories for four data sets. The image characteristics and BI-RADS categories of the four data sets were analyzed by another radiologist. The final diagnosis was made on the basis of pathologic findings. Values for area under the receiver operating curve (AUC), sensitivity, specificity and accuracy were compared among the data sets. The AUC of B-mode US combined with both color Doppler US and SE was greater than that of B-mode US alone (0.666 vs. 0.828) (p = 0.011). The specificity of making the decision for biopsy increased from 6.5% to 38.7% when B-mode US was combined with color Doppler and SE, without a statistically significant change in sensitivity (p < 0.001). Combined use of color Doppler and SE could improve the diagnostic value of B-mode US in distinguishing benign from malignant non-mass breast lesions and the specificity of making the decision for biopsy of non-mass breast lesions. (C) 2017 World Federation for Ultrasound in Medicine & Biology.