rTMS/iTBS and Cognitive Rehabilitation for Deficits Associated With TBI and PTSD: A Theoretical Framework and Review.
rTMS/iTBS and Cognitive Rehabilitation for Deficits Associated With TBI and PTSD: A Theoretical Framework and Review.
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DOI：
10.1176/appi.neuropsych.21090227
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发表时间：
2022-07
期刊：
影响因子：
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通讯作者：
André Lindsey;R. Ellison;A. Herrold;Alexandra L. Aaronson;S. Kletzel;Monica Stika;A. Guernon;Theresa L Bender Pape
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文献类型：
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作者：
André Lindsey;R. Ellison;A. Herrold;Alexandra L. Aaronson;S. Kletzel;Monica Stika;A. Guernon;Theresa L Bender Pape
创伤性脑损伤（TBI）引起的认知和心理缺陷的康复仍然是卫生保健领域的一个关注领域。常见的并发精神障碍，如重度抑郁症和创伤后应激障碍，在试图补救认知后遗症时会造成额外的障碍。有越来越多的需要程序，将产生一致的收益表明功能恢复。间歇性θ波刺激（iTBS）是一种重复经颅磁刺激，具有作为一种工具的潜力，可以定制以帮助认知过程并支持功能增益。iTBS的使用使得能够直接刺激期望的神经系统。iTBS，结合行为干预（例如，认知康复、心理治疗），可以在促进认知恢复和适应方面获得额外的成功。本理论综述的目的是说明iTBS的技术和生理方面如何增强TBI患者其他形式的神经康复。未来对iTBS组合干预的研究有可能转化为其他复杂的神经精神疾病。
Rehabilitation of cognitive and psychosocial deficits resulting from traumatic brain injury (TBI) continues to be an area of concern in health care. Commonly co-occurring psychiatric disorders, such as major depressive disorder and posttraumatic stress disorder, create additional hurdles when attempting to remediate cognitive sequelae. There is increased need for procedures that will yield consistent gains indicative of recovery of function. Intermittent theta-burst stimulation (iTBS), a form of repetitive transcranial magnetic stimulation, has potential as an instrument that can be tailored to aid cognitive processes and support functional gains. The use of iTBS enables direct stimulation of desired neural systems. iTBS, performed in conjunction with behavioral interventions (e.g., cognitive rehabilitation, psychotherapy), may result in additive success in facilitating cognitive restoration and adaptation. The purpose of this theoretical review is to illustrate how the technical and physiological aspects of iTBS may enhance other forms of neurorehabilitation for individuals with TBI. Future research on combinatorial iTBS interventions has the potential to translate to other complex neuropsychiatric conditions.