An Automated Mouse Tail Vascular Access System by Vision and Pressure Feedback.
An Automated Mouse Tail Vascular Access System by Vision and Pressure Feedback.
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DOI：
10.1109/tmech.2014.2360886
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发表时间：
2015-08
期刊：
影响因子：
--
通讯作者：
Tsao TC
中科院分区：
文献类型：
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作者：
Chang YC;Berry-Pusey B;Yasin R;Vu N;Maraglia B;Chatziioannou AX;Tsao TC
本文开发了一种新的基于视觉的静脉和针头检测方法以及实时压力反馈的自动血管接入系统(A-VAS)，用于小鼠药物递送。小鼠尾静脉注射是临床前影像应用的常规步骤，但也是关键步骤。由于静脉直径较小，以及尾毛、色素沉着和鳞片等外界干扰，识别静脉位置很困难，手动注射通常导致重复性较差。为了提高注射的准确性、一致性、安全性和处理时间，开发了A-VAS，以克服静脉检测噪声抑制、针跟踪的稳健性以及与机电系统的视觉伺服集成方面的困难。
This paper develops an automated vascular access system (A-VAS) with novel vision-based vein and needle detection methods and real-time pressure feedback for murine drug delivery. Mouse tail vein injection is a routine but critical step for preclinical imaging applications. Due to the small vein diameter and external disturbances such as tail hair, pigmentation, and scales, identifying vein location is difficult and manual injections usually result in poor repeatability. To improve the injection accuracy, consistency, safety, and processing time, A-VAS was developed to overcome difficulties in vein detection noise rejection, robustness in needle tracking, and visual servoing integration with the mechatronics system.