DDT reintroduction for malaria control: the cost-benefit debate for public health
DDT reintroduction for malaria control: the cost-benefit debate for public health
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DOI：
10.1590/s0102-311x2007001200004
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发表时间：
2007-12-01
期刊：
影响因子：
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通讯作者：
Meyer, Armando
中科院分区：
文献类型：
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作者：
Guimarães, Raphael Mendonça;Asmus, Carmen Ildes Rodrigues Fróes;Meyer, Armando
DDT是一种持久性杀虫剂，从20世纪40年代到20世纪70年代在世界范围内广泛使用，随后在美国和其他国家被禁止使用。其大部分毒性作用在急性形式下并未观察到，但在长期接触后尤其如此。这些长期问题包括生殖影响，其影响根据个体暴露的时间而变化。本研究的目的是回顾滴滴涕对生殖的主要毒理学影响，按生理暴露期分层，并根据这些影响的程度，讨论根据具体定义的病媒控制标准重新引入滴滴涕的成本效益关系。
DDT is a persistent insecticide that was widely used in the world from the 1940s until the 70s, when it was banned in the United States and other countries. Most of its toxic effects are not observed in the acute forms, but particularly after chronic exposure. These long-term issues include reproductive effects, varying according to the time of life in which the individuals were exposed. The aims of the current study were to review the principal toxicological effects of DDT on reproduction, stratifying by physiological periods of exposure, and based on the magnitude of these effects, to discuss the cost-benefit relationship of reintroducing DDT with the specifically defined vector control criteria.