A Novel Device for the Evaluation of Hemostatic Function in Critical Care Settings.
A Novel Device for the Evaluation of Hemostatic Function in Critical Care Settings.
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DOI：
10.1213/ane.0000000000001413
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发表时间：
2016-12
影响因子：
5.7
通讯作者：
Viola F
中科院分区：
文献类型：
--
作者：
Ferrante EA;Blasier KR;Givens TB;Lloyd CA;Fischer TJ;Viola F
大的外科手术经常导致显著的术中和术后出血。确定出血原因的能力有可能减少血液制品的输血并改善患者护理。我们介绍了一种新型器械，即Quantra™止血分析仪，其设计用于自动、快速、近距离患者监测止血。Quantra基于SEER声流变仪，这是一种专有技术，使用超声测量凝血过程中全血粘弹性变化引起的凝血时间和凝块硬度。我们提供了该技术的内部验证和分析性能测试结果，并证明了表征止血关键功能组件的能力。
Major surgical procedures often result in significant intra and postoperative bleeding. The ability to identify the cause of the bleeding has the potential to reduce the transfusion of blood products and improve patient care. We present a novel device, the Quantra™ Hemostasis Analyzer, which has been designed for automated, rapid, near patient monitoring of hemostasis. The Quantra is based on SEER Sonorheometry, a proprietary technology that uses ultrasound to measure clot time and clot stiffness from changes in viscoelastic properties of whole blood during coagulation. We present results of internal validation and analytical performance testing of the technology and demonstrate the ability to characterize the key functional components of hemostasis.