Poor premorbid adjustment and CT scan abnormalities in chronic schizophrenia.
Poor premorbid adjustment and CT scan abnormalities in chronic schizophrenia.
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慢性精神分裂症的病前调整不良和 CT 扫描异常。
DOI：
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发表时间：
1980
影响因子：
17.7
通讯作者：
R. Wyatt
中科院分区：
文献类型：
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作者：
D. Weinberger;E. Cannon;S. Potkin;R. Wyatt
采用一种新的量表对51例慢性精神分裂症患者的病前适应情况进行了回顾分析。那些有CT证据提示脑萎缩的患者病前得分明显低于那些扫描正常的患者，尤其是在儿童时期。这一发现进一步支持了慢性精神分裂症患者CT表现的临床相关性，并暗示了一个发生在发育早期的神经病理过程。
The authors evaluated the premorbid adjustment of 51 chronic schizophrenic patients by retrospective chart analysis using a novel scale. Those patients with CT evidence suggestive of brain atrophy had significantly worse premorbid scores, particularly during childhood, than did the patients with normal scans. This finding provides further support for the clinical relevance of CT findings in chronic schizophrenic patients and implicates a neuropathological process that occurs early in development.