The influence of coping and depression on abstinence from illicit drug use in methadone-maintained patients
The influence of coping and depression on abstinence from illicit drug use in methadone-maintained patients
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DOI：
10.1081/ada-100100252
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发表时间：
2000-01-01
影响因子：
2.7
通讯作者：
Margolin, A
中科院分区：
文献类型：
--
作者：
Avants, SK;Warburton, LA;Margolin, A
维持美沙酮的类阿片依赖患者使用非法药物损害了美沙酮维持治疗的益处。由于补充药理学方法取得的成功有限，因此重要的是要确定与药物使用相关的心理机制，这些机制可能有助于开发更有效的治疗方法。为了调查这个问题，目前的研究评估了307例美沙酮维持患者的应对和抑郁，发现对回避应对策略的依赖，最明显的是抑郁症患者。在12周的应对技能培训干预后实现禁欲的患者减少了回避型应对策略的使用。6个月随访时的药物使用与治疗期间的获益有关，特别是认知回避减少、抑郁减少和治疗期间无药物周数。
Use of illicit drugs by opioid-dependent patients maintained on methadone undermines the benefits of methadone maintenance treatment. Because supplemental pharmacologic approaches have met with limited success, it is important to identify psychological mechanisms associated with drug use that potentially could contribute to the development of more effective treatments. To investigate this issue, the current study assessed coping and depression in 307 methadone-maintained patients and found a reliance on avoidant coping strategies, most notably by depressed patients. Patients who achieved abstinence following a 12-week coping skills training intervention decreased the use of avoidant coping strategies. Drug use at the 6-month follow-up was related to gains made during treatment, specifically reduced cognitive avoidance, reduced depression, and number of drug-free weeks during treatment.