Diagnosis and economic consequences of triclabendazole resistance in Fasciola hepatica in a sheep flock in south-east Scotland
Diagnosis and economic consequences of triclabendazole resistance in Fasciola hepatica in a sheep flock in south-east Scotland
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DOI：
10.1136/vr.c5332
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发表时间：
2011-02-12
影响因子：
2.2
通讯作者：
Scott, P. R.
中科院分区：
文献类型：
--
作者：
Sargison, N. D.;Scott, P. R.
在过去十年里，与降雨增加或局部洪水有关的英国肝片吸虫病的地区性、季节性和严重性都发生了明确的变化，引发了关于气候变化有害影响的辩论。因此，在传统上存在吸虫的地区，对肝片吸虫病的有效管理变得困难，导致羊和牛的生产严重损失。与此同时，在东部地区，疾病意外爆发，导致产量损失和对福利的担忧。这份病例报告描述了苏格兰东南部一群商业羊群中的肝片吸虫病的经济后果。在制定经济上可持续的控制战略的背景下，讨论了三氯苯达唑耐药性的诊断和后果。
Over the past decade, definite changes have been recorded in the regional prevalence, seasonality and severity of fasciolosis in the UK, related to increased rainfall, or localised flooding, prompting debate about the deleterious effects of climate change. As a consequence, effective management of fasciolosis has become problematic in areas where fluke traditionally exists, leading to serious loss of production in sheep and cattle. Meanwhile, in eastern districts, there have been unexpected outbreaks of disease, resulting in production losses and concerns about welfare. This case report describes the economic consequences of fasciolosis in a commercial sheep flock in south-east Scotland. The diagnosis and consequences of triclabendazole resistance are discussed, in the context of developing economically sustainable control strategies.