Fabrication and Optimization of Fiber-Based Lithium Sensor: A Step toward Wearable Sensors for Lithium Drug Monitoring in Interstitial Fluid.
Fabrication and Optimization of Fiber-Based Lithium Sensor: A Step toward Wearable Sensors for Lithium Drug Monitoring in Interstitial Fluid.
复制标题
基于纤维的锂传感器的制造和优化：迈向用于组织液中锂药物监测的可穿戴传感器的一步。
作者：
Mona N. Sweilam;J. Varcoe;C. Crean
采用简单、可重复的浸涂技术，采用低成本棉花制成了一种微型、柔性纤维锂传感器。这种锂传感器非常适合即用型可穿戴应用，并且可以直接使用，无需传统离子选择性电极通常所需的预处理步骤。该传感器在较宽的 Li+ 浓度范围内具有稳定、快速和准确的响应，涵盖了人体血清中锂的临床有效浓度和毒性浓度限制。即使存在高浓度的 Na+ 离子，该传感器对人血浆中的 Li+ 也具有选择性。这种新颖的传感器概念代表了可穿戴传感器技术的重大进步，该技术将针对皮下锂药物监测。
A miniaturized, flexible fiber-based lithium sensor was fabricated from low-cost cotton using a simple, repeatable dip-coating technique. This lithium sensor is highly suited for ready-to-use wearable applications and can be used directly without the preconditioning steps normally required with traditional ion-selective electrodes. The sensor has a stable, rapid, and accurate response over a wide Li+ concentration range that spans over the clinically effective and the toxic concentration limits for lithium in human serum. The sensor is selective to Li+ in human plasma even in the presence of a high concentration of Na+ ions. This novel sensor concept represents a significant advance in wearable sensor technology which will target lithium drug monitoring from under the skin.
影响因子：
7.4
作者：
Bakker, E;Pretsch, E;Bühlmann, P
通讯作者：
Bühlmann, P