PHARMACOKINETICS OF CAFFEINE DURING AND AFTER PREGNANCY

PHARMACOKINETICS OF CAFFEINE DURING AND AFTER PREGNANCY
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DOI：
10.1159/000457332
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发表时间：
1983-01-01
期刊：
DEVELOPMENTAL PHARMACOLOGY AND THERAPEUTICS
影响因子：
--
通讯作者：
FAUCON, G
FAUCON, G
中科院分区：
其他
文献类型：
--
作者：
BRAZIER, JL;RITTER, J;FAUCON, G

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本文测定了9名孕妇和4名产后4天妇女的咖啡因药代动力学参数。在孕妇中可以看到咖啡因消除的显着延长。正常的药代动力学参数似乎在产后4天即可恢复。在这两种情况下测量类固醇激素（雌三醇，雌二醇和孕酮）。
The pharmacokinetic parameters of caffeine were measured in 9 pregnant women and 4 women 4 days post partum. A significant prolongation of caffeine elimination in pregnant women is seen. Normal pharmacokinetic parameters seem to be restored as soon as 4 days post partum. Steroids hormones (estriol, estradiol and progesterone) were measured in both cases.