Natural selection favors a newly derived timeless allele in Drosophila melanogaster
Natural selection favors a newly derived timeless allele in Drosophila melanogaster
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DOI：
10.1126/science.1138412
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发表时间：
2007-06-29
期刊：
影响因子：
56.9
通讯作者：
Costa, Rodolfo
中科院分区：
文献类型：
--
作者：
Tauber, Eran;Zordan, Mauro;Costa, Rodolfo
昼夜节律和其他自然时钟样的内源性节律可能已经进化到预期环境中的规律性时间变化。我们报告说，突变的昼夜节律钟基因永恒的果蝇已经出现，并通过自然选择传播相对最近在欧洲。我们发现，当引入到不同的遗传背景，自然和人工等位基因的永恒的基因影响滞育的发病率在响应光和温度的变化。自然突变等位基因改变了一个重要的生活史特征，可能会增强苍蝇对季节性条件的适应。
Circadian and other natural clock-like endogenous rhythms may have evolved to anticipate regular temporal changes in the environment. We report that a mutation in the circadian clock gene timeless in Drosophila melanogaster has arisen and spread by natural selection relatively recently in Europe. We found that, when introduced into different genetic backgrounds, natural and artificial alleles of the timeless gene affect the incidence of diapause in response to changes in light and temperature. The natural mutant allele alters an important life history trait that may enhance the fly's adaptation to seasonal conditions.