Population-Attributable Fractions of Axis I and Axis II Mental Disorders for Suicide Attempts: Findings From a Representative Sample of the Adult, Noninstitutionalized US Population
Population-Attributable Fractions of Axis I and Axis II Mental Disorders for Suicide Attempts: Findings From a Representative Sample of the Adult, Noninstitutionalized US Population
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DOI：
10.2105/ajph.2010.192252
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发表时间：
2010-12-01
影响因子：
12.7
通讯作者：
Robinson, Jennifer
中科院分区：
文献类型：
--
作者：
Bolton, James M.;Robinson, Jennifer
目标。我们的目的是通过在全国代表性样本中研究人口归因分数（paf）来确定可归因于个体I轴和II轴精神障碍的自杀企图百分比。数据来自全国酒精及相关疾病流行病学调查第二波（NESARC; 2004-2005），这是一项美国精神疾病大型调查（N = 34653）。我们使用多变量逻辑回归来比较有和没有自杀企图史的个体，包括第四版《精神障碍诊断与统计手册》、第一轴障碍（焦虑、情绪、精神病、酒精和药物障碍）和所有10种第二轴人格障碍。计算每种疾病的paf。在我们在模型中检查的25种障碍中，有4种障碍具有显著高的PAF值：重度抑郁症（PAF = 26.6%； 95%可信区间[CI] = 20.1, 33.2），边缘型人格障碍（PAF = 18.1%; 95% CI = 13.4, 23.5），尼古丁依赖（PAF = 8.4%; 95% CI = 3.4, 13.7）和创伤后应激障碍（PAF = 6.3%; 95% CI = 3.2, 10.0）。我们的研究结果为普通人群中精神障碍和自杀企图之间的关系提供了新的见解。尽管许多精神疾病与自杀倾向的增加有关，但自杀倾向的上升主要归因于精神疾病的存在。
Objectives. We aimed to determine the percentage of suicide attempts attributable to individual Axis I and Axis II mental disorders by studying population-attributable fractions (PAFs) in a nationally representative sample.Methods. Data were from the National Epidemiologic Survey on Alcohol and Related Conditions Wave 2 (NESARC; 2004-2005), a large (N = 34 653) survey of mental illness in the United States. We used multivariate logistic regression to compare individuals with and without a history of suicide attempt across Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Axis I disorders (anxiety, mood, psychotic, alcohol, and drug disorders) and all 10 Axis II personality disorders. PAFs were calculated for each disorder.Results. Of the 25 disorders we examined in the model, 4 disorders had notably high PAF values: major depressive disorder (PAF = 26.6%; 95% confidence interval [CI] = 20.1, 33.2), borderline personality disorder (PAF = 18.1%; 95% CI = 13.4, 23.5), nicotine dependence (PAF = 8.4%; 95% CI = 3.4, 13.7), and posttraumatic stress disorder (PAF = 6.3%; 95% CI = 3.2, 10.0).Conclusions. Our results provide new insight into the relationships between mental disorders and suicide attempts in the general population. Although many mental illnesses were associated with an increased likelihood of suicide attempt, elevated rates of suicide attempts were mostly attributed to the presence of 4 disorders.