ELECTRON MICROSCOPE STUDY OF DEVELOPING TASTE BUD IN RAT FUNGIFORM PAPILLA
ELECTRON MICROSCOPE STUDY OF DEVELOPING TASTE BUD IN RAT FUNGIFORM PAPILLA
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DOI：
10.1016/0012-1606(65)90040-0
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发表时间：
1965-01-01
影响因子：
2.7
通讯作者：
FARBMAN, AI
中科院分区：
文献类型：
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作者：
FARBMAN, AI
本文对孕16天至生后28天大鼠舌菌状乳头和味蕾的发育进行了电镜观察。为便于描述，将发育过程任意分为5个阶段。菌状乳头，包含上皮和结缔组织成分，首先出现在妊娠第16天（第1阶段）。随后是结缔组织核心内的神经纤维的出现（阶段2），然后是神经突起进入游离表面处的上皮（阶段3）。后者与神经突起附近的上皮细胞中引人注目的囊泡簇的出现有关。几天后，正在形成的味蕾中的细胞已经开始分化成3种不同的类型（阶段4）;最后，第4种细胞类型在大约建立味孔的时候出现（阶段5）。
A serial electron microscope study was performed on developing fungiform papillae and taste buds from tongues of rats ranging in age from the 16th day of gestation to 28 days postnatally. For convenience of description the developmental process was arbitrarily divided into 5 stages. Fungiform papillae, containing both epithelial and connective tissue components, appear first on the 16th day of gestation (stage 1). This is followed by the appearance of nerve fibers within the connective tissue core (stage 2) and then the entrance of nerve processes into the epithelium at the free surface (stage 3). The latter is associated with the striking appearance of clusters of vesicles in the epithelial cells adjacent to nerve processes. Several days later, the cells in the forming taste bud have begun to differentiate into 3 different types (stage 4); finally, a 4th cell type appears at about the time that the taste pore is established (stage 5).