Synthesis of multicompartment nanoparticles of a triblock terpolymer by seeded RAFT polymerization
Synthesis of multicompartment nanoparticles of a triblock terpolymer by seeded RAFT polymerization
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DOI：
10.1039/c5py01041a
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发表时间：
2015-08
影响因子：
4.6
通讯作者：
X. He;Y. Qu;Chengqiang Gao;Wangqing Zhang
中科院分区：
文献类型：
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作者：
X. He;Y. Qu;Chengqiang Gao;Wangqing Zhang
采用RAFT种子聚合法制备了聚（N，N-二甲基丙烯酰胺）-b-聚苯乙烯-b-聚（4-乙烯基吡啶）（PDMA-b-PS-b-P4 VP）三嵌段嵌段共聚物的多室纳米粒，该纳米粒含有聚苯乙烯（PS）核、分散在PS核上的聚（4-乙烯基吡啶）（P4 VP）微相和溶剂化的聚（N，N-二甲基丙烯酰胺）（PDMA）冠。在该种子RAFT聚合之后，首先通过分散RAFT聚合制备聚（N，N-二甲基丙烯酰胺）-b-聚苯乙烯的种子纳米颗粒，然后通过种子RAFT聚合将P4 VP嵌段引入到种子纳米颗粒上，以制备包含PS核和P4 VP和PDMA的混合冠的PDMA-b-PS-b-P4 VP的冠-核纳米颗粒。当PDMA-b-PS-b-P4 VP的冠核纳米颗粒分散在水中时，被相邻PDMA链隔离的P4 VP链存款在PS核上形成离散的P4 VP微相，并且它们转化为多室纳米颗粒。结果表明，随着P4 VP嵌段聚合度的增加，PS核上P4 VP微相的尺寸增大。这种接种RAFT聚合被认为是制备嵌段共聚物多室纳米颗粒的有效方法。
Seeded RAFT polymerization is proposed to prepare multicompartment nanoparticles of the poly(N,N-dimethylacrylamide)-b-polystyrene-b-poly(4-vinylpyridine) (PDMA-b-PS-b-P4VP) triblock terpolymer, which contain a polystyrene (PS) core, discrete poly(4-vinylpyridine) (P4VP) microphases on the PS core, and a solvated poly(N,N-dimethylacrylamide) (PDMA) corona. Following this seeded RAFT polymerization, the seed nanoparticles of poly(N,N-dimethylacrylamide)-b-polystyrene are initially prepared through dispersion RAFT polymerization, and then the P4VP block is introduced onto the seed nanoparticles by seeded RAFT polymerization to prepare the corona–core nanoparticles of PDMA-b-PS-b-P4VP containing a PS core and a mixed corona of P4VP and PDMA. When the corona–core nanoparticles of PDMA-b-PS-b-P4VP are dispersed in water, the P4VP chains, which are segregated by the neighboring PDMA chains, deposit on the PS core to form the discrete P4VP microphases on the PS core, and they convert into multicompartment nanoparticles. It is found that the size of the P4VP microphases on the PS core increases with the polymerization degree of the P4VP block. This seeded RAFT polymerization is believed to be a valid method to prepare block copolymer multicompartment nanoparticles.