Sesquiterpenes from Chloranthus japonicus.
Sesquiterpenes from Chloranthus japonicus.
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DOI：
10.1021/np100504m
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发表时间：
2011-01
影响因子：
5.1
通讯作者：
Qiu-Hong Wang;H. Kuang;Bingyou Yang;Yong-Gang Xia;Junsong Wang;L. Kong
中科院分区：
文献类型：
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作者：
Qiu-Hong Wang;H. Kuang;Bingyou Yang;Yong-Gang Xia;Junsong Wang;L. Kong
从金莲花全草乙醇提取物的乙酸乙酯可溶萃取物中分离得到8个新的倍半萜内酯(氯菊酯A-E，1-5，氯菊酯，6，氯菊醇，7，和氯菊内酯，8)。通过光谱数据分析，确定了1-8的结构和相对构型。所有获得的分离株都被评估了它们对一小部分癌细胞株的细胞毒活性。
Eight new sesquiterpene lactones (chlorajapolides A-E, 1-5, chlorajaposide, 6, chlorajaponol, 7, and chloraeudolide, 8) were isolated from an ethyl acetate-soluble partition of the ethanol extract of the whole plants of Chloranthus japonicus. The structures and relative configurations of 1-8 were established on the basis of spectroscopic data analysis. All isolates obtained were evaluated for their cytotoxic activity against a small panel of cancer cell lines.