Improved Sleep MRI at 3 Tesla in Patients With Obstructive Sleep Apnea

Improved Sleep MRI at 3 Tesla in Patients With Obstructive Sleep Apnea
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DOI:
10.1002/jmri.24029
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发表时间:
2013-11-01
影响因子:
4.4
通讯作者:
Pauly, Kim Butts
Pauly, Kim Butts
中科院分区:
医学2区
文献类型:
--
作者:
Shin, Lewis K.;Holbrook, Andrew B.;Pauly, Kim Butts

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目的描述一种3Tesla(T)同步多平面显示阻塞性睡眠呼吸暂停患者上呼吸道塌陷的实时MR成像平台,以促进自然睡眠,重点是侧壁显示。材料与方法建立了一个用于睡眠MR成像的实时成像平台,该平台使用笛卡尔、部分k空间梯度回波序列,其固有时间分辨率为每2个S 3个独立切片。该系统在5名患有多导睡眠图证实的阻塞性睡眠呼吸暂停的受试者中进行了测试,同步采集呼吸努力和口腔-鼻腔气流数据。结果启动并维持睡眠以允许演示睡眠诱导的上呼吸道塌陷,如在3T时使用实时睡眠磁共振成像平台时的两名受试者所示。侧壁塌陷不能单独在正中矢状位成像上显示,而在多平面冠状和轴位成像平面上表现最好。结论我们的专用睡眠MR成像平台允许持续白噪声的声学环境,这有利于3T阻塞性睡眠呼吸暂停患者的睡眠开始和睡眠维持。呼吸暂停发作,特别是侧壁,更准确地描述了同步的多平面采集。J·马根。雷森。《影像》2013;38:1261-1266。(C)2013年威利期刊公司。
PurposeTo describe a real-time MR imaging platform for synchronous, multi-planar visualization of upper airway collapse in obstructive sleep apnea at 3 Tesla (T) to promote natural sleep with an emphasis on lateral wall visualization.Materials and MethodsA real-time imaging platform was configured for sleep MR imaging which used a cartesian, partial k-space gradient-echo sequence with an inherent temporal resolution of 3 independent slices every 2 s. Combinations of axial, mid-sagittal, and coronal scan planes were acquired. The system was tested in five subjects with polysomnography-proven obstructive sleep apnea during sleep, with synchronous acquisition of respiratory effort and combined oral-nasal airflow data.ResultsSleep was initiated and maintained to allow demonstration of sleep-induced, upper airway collapse as illustrated in two subjects when using a real-time, sleep MR imaging platform at 3T. Lateral wall collapse could not be visualized on mid-sagittal imaging alone and was best characterized on multiplanar coronal and axial imaging planes.ConclusionOur dedicated sleep MR imaging platform permitted an acoustic environment of constant white noise which was conducive to sleep onset and sleep maintenance in obstructive sleep apnea patients at 3T. Apneic episodes, specifically the lateral walls, were more accurately characterized with synchronous, multiplanar acquisitions. J. Magn. Reson. Imaging 2013;38:1261-1266. (c) 2013 Wiley Periodicals, Inc.