Effects of Hair Metals on Body Weight in Iranian Children Aged 20 to 36 Months
Effects of Hair Metals on Body Weight in Iranian Children Aged 20 to 36 Months
复制标题
DOI：
--
复制
发表时间：
2017-07
影响因子：
1.4
通讯作者：
M. Vigeh;K. Yokoyama;Takehisa Matsukawa;A. Shinohara;M. Shariat;K. Ohtani
中科院分区：
文献类型：
--
作者：
M. Vigeh;K. Yokoyama;Takehisa Matsukawa;A. Shinohara;M. Shariat;K. Ohtani
背景资料：虽然接触许多有毒金属的水平最近有所下降，但这些金属对儿童生长发育的不利影响仍然是一个严重的公共卫生问题。研究方法：本研究于2012年9月至2013年3月在德黑兰医科大学（德黑兰，伊朗）附属的三家教学医院进行。为了研究金属与儿童生长之间的关系，对174名年龄在20至36个月的儿童的头发中锌和几种潜在有毒金属（铅、镉、锑、钴和钼）的浓度进行了测定。结果如下：体重较低百分位数儿童的头发钴浓度显著高于体重较高百分位数儿童（分别为0.026 ± 0.04和0.015 ± 0.01 μg/g）（P<0.05）。女孩头发中铅、钴、锑的含量分别为（8.08 ± 8.7）μg/g、（0.026 ± 0.03）μg/g和（0.188 ± 0.29）μ g/g，显著高于男孩（4.92 ± 5.6）μg/g、（0.102 ± 0.12）μg/g（P<0.05）。儿童头发中的铅和其他金属之间也有显着的相关性。结论：性别可能在金属的吸收和/或积累中起重要作用。当我们研究儿童的金属毒性时，应该考虑到这一点。
Background: Although the level of exposure to many toxic metals decreased recently, the adverse effects of these metals on children’s growth and development remain a serious public health issue. Methods: The present study was conducted in three teaching hospitals affiliated with Tehran University of Medical Sciences (Tehran, Iran) from Sep 2012 to Mar 2013. To study the relationship between metals and childhood growth, concentrations of zinc and several potentially toxic metals (lead, cadmium, antimony, cobalt, and molybdenum) were measured in scalp hair for 174 children, aged 20 to 36 months. Results: The hair concentrations of cobalt were significantly (P<0.05) higher in children at the lower percentile of weight than in higher-weight children (0.026 ± 0.04 vs. 0.015 ± 0.01 μg/g, respectively). Hair contents of lead, cobalt, and antimony were significantly higher (P<0.05) in girls than in boys (8.08 ± 8.7 vs. 4.92 ± 5.6 μg/g for lead, 0.026 ± 0.03 vs. 0.16 ± 0.02 μg/g for cobalt, and 0.188 ± 0.29 vs. 0.102 ± 0.12 μg/g for antimony). There were also significant correlations between lead and other metals in the children’s hair. Conclusion: Gender may play a significant role in absorption and/or accumulation of metals. It should be considered when we study metal toxicity in children.