Comparison of 180 degrees and 360 degrees data acquisition for determination of left ventricular function from gated myocardial perfusion tomography and gated blood pool tomography.
Comparison of 180 degrees and 360 degrees data acquisition for determination of left ventricular function from gated myocardial perfusion tomography and gated blood pool tomography.
复制标题
通过门控心肌灌注断层扫描和门控血池断层扫描确定左心室功能的 180 度和 360 度数据采集的比较。
DOI：
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发表时间：
2003
影响因子：
9.1
通讯作者：
A. Bossuyt
中科院分区：
文献类型：
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作者：
C. Vanhove;P. Franken;M. Defrise;A. Bossuyt
本研究的目的是解决使用门控心肌灌注断层扫描（gMPT）和门控血池断层扫描（gBPT）进行左心室射血分数（LVEF）和左心室容积测量的180度与360度数据收集的问题。30例已知患有冠状动脉疾病的患者随机注射925 MBq的锝-99m tetrofosmin，并在2天内注射740 MBq的（99 m）Tc标记的人血清白蛋白。使用360度数据收集采集gMPT和gBPT，并使用所有采集的投影图像和单独使用仅从45度LPO至45度RAO采集的投影图像通过滤波反投影重建。为了具有相同的全局计数密度，在重建之前使用二项式偏差重新分布360度数据集中的计数。沿左心室长轴沿着重新定向后，使用全自动算法计算LVEF和左心室容积。28例患者还在gBPT的同一天接受了平面放射性核素心血管造影（PRNA）。对于gMPT研究，180度数据收集与360度数据收集之间的相关性极佳（r>0.98）。Bland-Altman分析显示，180度和360度之间的系统性和随机性差异较小（<6%）。对于gBPT研究，180度数据收集和360度数据收集之间的相关性非常好（r>0.93）。然而，Bland-Altman分析显示系统差异为26%，随机差异为17%。当使用PRNA作为参考时，使用180度数据获取的gMPT获得最佳结果，而使用180度数据获取的gBPT获得最差结果。总之，当根据gMPT评价LVEF和左心室容积时，可以使用180度或360度轨道。但是，当从gBPT评价LVEF和左心室容积时，建议进行360度数据采集。
The purpose of this study was to address the issue of 180 degrees versus 360 degrees data collection for left ventricular ejection fraction (LVEF) and left ventricular volume measurements using gated myocardial perfusion tomography (gMPT) and gated blood pool tomography (gBPT). Thirty patients with known coronary artery disease were injected in a random sequence with 925 MBq of technetium-99m tetrofosmin and, within 2 days, with 740 MBq of (99m)Tc-labelled human serum albumin. gMPT and gBPT were acquired using 360 degrees data collection and reconstructed by filtered backprojection using all the acquired projection images and separately using only projection images acquired from 45 degrees LPO to 45 degrees RAO. In order to have the same global count densities, the counts in the 360 degrees data set were redistributed using binomial deviates just before reconstruction. After reorientation along the left ventricular long axis, LVEF and left ventricular volumes were calculated using fully automatic algorithms. Twenty-eight patients also underwent planar radionuclide angiocardiography (PRNA) on the same day as the gBPT. For the gMPT studies, the correlation between 180 degrees data collection and 360 degrees data collection was excellent ( r>0.98). Bland-Altman analysis revealed small systematic and random differences (<6%) between 180 degrees and 360 degrees. For the gBPT studies, the correlation between 180 degrees data collection and 360 degrees data collection was very good ( r>0.93). However, Bland-Altman analysis revealed systematic differences of 26% and random differences of 17%. When PRNA was used as a reference, the best results were obtained with gMPT acquired using 180 degrees data, while the worst results were obtained with gBPT acquired using 180 degrees data. In conclusion, when evaluating LVEF and left ventricular volumes from gMPT, either 180 degrees or 360 degrees orbits can be used. However, 360 degrees data acquisition is recommended when evaluating LVEF and left ventricular volumes from gBPT.