Synthesis and bioactive properties of macroporous nanoscale SiO2-CaO-P2O5 bioactive glass
Synthesis and bioactive properties of macroporous nanoscale SiO2-CaO-P2O5 bioactive glass
复制标题
大孔纳米SiO2-CaO-P2O5生物活性玻璃的合成及生物活性性能
DOI：
10.1016/j.jnoncrysol.2009.09.029
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发表时间：
2009-12-15
影响因子：
3.5
通讯作者：
Fang, Liming
中科院分区：
文献类型：
--
作者：
Lei, Bo;Chen, Xiaofeng;Fang, Liming
采用溶胶-凝胶共模板法制备了SiO2-CaO-P2 O 5体系大孔纳米生物活性玻璃。孔隙率仪分析表明，合成的生物活性玻璃（BG）的孔隙率为85%，并表现出多峰孔径分布，纳米孔（10- 40 nm）和大孔（100 nm-10 μ m）。形貌和结构表征表明，孔壁宽约250 nm，长约1 μ m，孔壁相互连通。体外生物活性测试表明，合成的块体BG具有更快的磷灰石层形成能力比传统的溶胶-凝胶BG。此外，沉积层被鉴定为羟基碳酸磷灰石，其类似于人骨的无机部分。(C)2009 Elsevier B. V.保留所有权利。
A macroporous nanoscale bulk bioactive glass (SiO2-CaO-P2O5 system) was prepared by sol-gel co-template method. Porosimeter analysis showed that the as-synthesized bioactive glasses (BGs) had a porosity of 85% and exhibited a multimodal pore size distribution, nanopores (10-40nm) and macropores (100 nm-10 mu m). Morphological and structural characterizations showed the pores were interconnected with pore walls of about 250 nm in width and I mu m in length. In vitro bioactivity test indicated that the as-synthesized bulk BGs exhibited faster apatite layer formation capability than the conventional sol-gel BGs. Additionally, the deposited layer was identified as hydroxycarbonate apatite, which is similar to the inorganic part of human bone. (C) 2009 Elsevier B.V. All rights reserved.