The interfascicular matrix enables fascicle sliding and recovery in tendon, and behaves more elastically in energy storing tendons.
The interfascicular matrix enables fascicle sliding and recovery in tendon, and behaves more elastically in energy storing tendons.
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DOI：
10.1016/j.jmbbm.2015.04.009
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发表时间：
2015-12
影响因子：
3.9
通讯作者：
Screen HRC
中科院分区：
文献类型：
--
作者：
Thorpe CT;Godinho MSC;Riley GP;Birch HL;Clegg PD;Screen HRC
虽然所有肌腱的主要功能是将力从肌肉传递到骨骼并定位四肢，但有些肌腱还可以作为能量储存，降低运动成本。能量储存肌腱经历极高的应变，并且需要能够有效地反冲以最大限度地储存和返回能量。在马前肢中，储存能量的浅指屈肌腱（SDFT）比位置性指伸肌总肌腱（CDET）具有更高的失效应变。然而，我们之前已经表明，这不是由于SDFT和CDET束（最大的肌腱亚基）的性质差异。相反，在SDFT中有更大的束间滑动能力，这有助于该特定肌腱的更大伸展。在本研究中，我们将SDFT和CDET的神经束和神经束间基质（IFM）暴露于循环载荷，然后进行失效测试。结果表明，IFM的力学行为不是不可逆变形的结果，但IFM能够承受循环载荷，并且在SDFT中比在CDET中更具弹性。我们还评估了老化对IFM性能的影响，表明IFM随着老化而抵抗重复载荷的能力降低，SDFT随着老化而变得更硬。这些结果提供了进一步的迹象表明，IFM是重要的有效功能，在能量储存肌腱，和年龄相关的改变，IFM可能会损害功能和易患老年肌腱损伤。束滑动使高水平的延伸，在能量储存肌腱。滑动力学是由束间矩阵（IFM）。我们评估了IFM的扩展和恢复。IFM的弹性和恢复是更大的能量储存肌腱。IFM在肌腱的储能功能中起着重要的作用。
While the predominant function of all tendons is to transfer force from muscle to bone and position the limbs, some tendons additionally function as energy stores, reducing the cost of locomotion. Energy storing tendons experience extremely high strains and need to be able to recoil efficiently for maximum energy storage and return. In the equine forelimb, the energy storing superficial digital flexor tendon (SDFT) has much higher failure strains than the positional common digital extensor tendon (CDET). However, we have previously shown that this is not due to differences in the properties of the SDFT and CDET fascicles (the largest tendon subunits). Instead, there is a greater capacity for interfascicular sliding in the SDFT which facilitates the greater extensions in this particular tendon. In the current study, we exposed fascicles and interfascicular matrix (IFM) from the SDFT and CDET to cyclic loading followed by a test to failure. The results show that IFM mechanical behaviour is not a result of irreversible deformation, but the IFM is able to withstand cyclic loading, and is more elastic in the SDFT than in the CDET. We also assessed the effect of ageing on IFM properties, demonstrating that the IFM is less able to resist repetitive loading as it ages, becoming stiffer with increasing age in the SDFT. These results provide further indications that the IFM is important for efficient function in energy storing tendons, and age-related alterations to the IFM may compromise function and predispose older tendons to injury. Fascicle sliding enables high levels of extension in energy storing tendons. Sliding mechanics are governed by the interfascicular matrix (IFM). We assessed IFM extension and recovery. IFM elasticity and recovery are greater in energy storing tendons. The IFM plays an important role in the function of energy storing tendons.