Efficient Immobilization of Cellulose Phenylcarbamate Bearing Alkoxysilyl Group onto Silica Gel by Intermolecular Polycondensation and Its Chiral Recognition
Efficient Immobilization of Cellulose Phenylcarbamate Bearing Alkoxysilyl Group onto Silica Gel by Intermolecular Polycondensation and Its Chiral Recognition
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DOI：
10.1246/cl.2006.1250
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发表时间：
2006-10
影响因子：
1.6
通讯作者：
T. Ikai;C. Yamamoto;M. Kamigaito;Y. Okamoto
中科院分区：
文献类型：
--
作者：
T. Ikai;C. Yamamoto;M. Kamigaito;Y. Okamoto
合成了含有少量3-（三乙氧基硅基）丙基残基的3，5-二甲基苯基氨基甲酸纤维素，并通过三乙氧基硅基的缩聚反应将其有效地固定在硅胶载体上用于高效液相色谱。该固定化手性填充材料（CPM）表现出与常规CPM一样高的手性识别性，并可用于多种洗脱剂。
Cellulose 3,5-dimethylphenylcarbamate bearing a small amount of 3-(triethoxysilyl)propyl residues was synthesized and effectively immobilized onto silica gel support for high-performance liquid chromatography by the polycondensation of triethoxysilyl groups. The immobilized chiral packing material (CPM) showed high chiral recognition as well as the conventional CPM prepared by coating the derivative onto silica gel, and can be used with a variety of eluents.