Distribution of stereospecific opiate receptor binding activity between subcellular fractions from ovine corpus striatum.
Distribution of stereospecific opiate receptor binding activity between subcellular fractions from ovine corpus striatum.
复制标题
绵羊纹状体亚细胞部分之间立体特异性阿片受体结合活性的分布。
DOI：
10.1016/0006-291x(80)90733-0
复制
发表时间：
1980
影响因子：
3.1
通讯作者：
Barnard,EA
中科院分区：
文献类型：
--
作者：
Glasel,JA;Venn,RF;Barnard,EA
本文报道了阿片配体埃托啡与绵羊中枢神经系统组织亚细胞组分的热力学结合常数。检查的是突触体、微粒体和髓鞘组分。在微粒体组分中，解离常数最小，结合能力最大。这些结果对阿片受体异质性和分离的未来工作具有影响。
The thermodynamic binding constants of the opiate ligand etorphine to subcellular fractions prepared from ovine central nervous system tissue are reported. Those examined were synaptosomal, microsomal and myelin fractions. The dissociation constant is smallest and the binding capacity greatest in the microsomal fraction. The results have implications concerning future work on opiate receptor heterogeneity and isolation.