Iridium/Chiral Diene-Catalyzed Asymmetric 1,6-Addition of Arylboroxines to α,β,γ,δ-Unsaturated Carbonyl Compounds
Iridium/Chiral Diene-Catalyzed Asymmetric 1,6-Addition of Arylboroxines to α,β,γ,δ-Unsaturated Carbonyl Compounds
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DOI：
10.1021/ja1034842
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发表时间：
2010-06-16
影响因子：
15
通讯作者：
Hayashi, Tamio
中科院分区：
文献类型：
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作者：
Nishimura, Takahiro;Yasuhara, Yuichi;Hayashi, Tamio
利用铱/手性二烯配合物，实现了芳基硼氧杂环戊烷对α,β,γ,δ -不饱和羰基化合物的铱催化不对称1,6 -加成反应，以高产率得到了具有90 - 99%对映选择性的δ -芳基化羰基化合物。
Iridium-catalyzed asymmetric 1,6-addition of arylboroxines to alpha,beta,gamma,delta-unsaturated carbonyl compounds to give delta-arylated carbonyl compounds in high yields with 90-99% enantioselectivity was realized by use of an iridium/chiral diene complex.