Chest Pain Characteristics and Gender in the Early Diagnosis of Acute Myocardial Infarction

Chest Pain Characteristics and Gender in the Early Diagnosis of Acute Myocardial Infarction
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DOI:
10.1007/s11886-014-0557-5
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发表时间:
2015-02-01
影响因子:
3.7
通讯作者:
Bittner, Vera
Bittner, Vera
中科院分区:
医学3区
文献类型:
--
作者:
Arora, Garima;Bittner, Vera

文献摘要

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急性心肌梗塞是男性和女性心血管疾病死亡的主要原因之一。胸痛通常被描述为胸闷、胸闷或挤压感,是急性心肌梗死患者最常见的症状。尽管急性心肌梗死的诊断通常基于表面心电图的典型变化和心脏生物标志物的变化,但仍需要更好地认识和理解性别对急性冠脉综合征或急性心肌梗死患者症状的影响。我们简要回顾了缺血症状的病理生理学,讨论了缺血症状因性别而变化的潜在机制,并总结了最近发表的解决缺血症状性别差异的出版物。
Acute myocardial infarction is one of the leading causes of cardiovascular disease mortality in both men and women. Chest pain, which is often described as chest pressure, tightness, or a squeezing sensation, is the most frequent symptom in patients presenting with acute myocardial infarction. Although the diagnosis of acute myocardial infarction is often based on typical changes on a surface electrocardiogram and on changes in cardiac biomarkers, there is a need to better recognize and understand the impact of sex on symptoms among patients presenting with acute coronary syndrome or acute myocardial infarction. We briefly review the pathophysiology of ischemic symptoms, discuss potential mechanisms for variation in ischemic symptoms by sex, and summarize recent publications that have addressed sex differences in ischemic symptoms.