Changes in blood ketone body ratio: their significance after major hepatic resection.
Changes in blood ketone body ratio: their significance after major hepatic resection.
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血酮体比率的变化：主要肝切除术后的意义。
DOI：
10.1001/archsurg.1981.01380180039008
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发表时间：
1981
影响因子：
--
通讯作者：
T. Tobe
中科院分区：
文献类型：
--
作者：
M. Ukikusa;K. Ozawa;Y. Shimahara;M. Asano;T. Nakatani;T. Tobe
研究了大体积肝切除后患者及家兔动脉血中乙酰乙酸与3-羟基丁酸酮体比值的变化。1例肝切除术成功的患者，术后血酮体比迅速下降后又恢复到术前水平；而在肝切除术不成功的患者中，血酮体比在手术后没有迅速下降。70%肝切除家兔，血酮体比在肝切除后9小时下降最大，随后逐渐恢复正常。兔肝切除70%后血酮体比与肝能电荷呈平行关系。血酮体比的测定对于评价残肝的能量状态是非常有用的。
Changes in the ratio of acetoacetate to 3-hydroxybutyrate (the ketone body ratio) in arterial blood were investigated after massive liver resection in patients and rabbits. In a patient who had had a successful hepatectomy, the blood ketone body ratio decreased rapidly after the operation and then returned to the preoperative level; whereas in a patient who had had an unsuccessful hepatectomy, the blood ketone body ratio did not decrease rapidly after the operation. In 70% hepatectomized rabbits, the blood ketone body ratio decreased maximally nine hours after hepatectomy and then returned gradually to a normal level. The blood ketone body ratio paralleled the hepatic energy charge after 70% hepatectomy in rabbits. The measurement of the blood ketone body ratio is very useful for evaluation of the energy status of the remnant liver.