Cell turnover in tissues of the long-lived ocean quahog Arctica islandica and the short-lived scallop Aequipecten opercularis
Cell turnover in tissues of the long-lived ocean quahog Arctica islandica and the short-lived scallop Aequipecten opercularis
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DOI：
10.1007/s00227-010-1408-6
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发表时间：
2010-02
期刊：
影响因子：
2.4
通讯作者：
J. Strahl;D. Abele
中科院分区：
文献类型：
--
作者：
J. Strahl;D. Abele
在两种双壳类物种的组织中研究了细胞增殖和凋亡：来自德国湾的北极岛（双壳类的年龄：33-98 年）和冰岛（7-148 年）和来自英吉利海峡的Aequipecten operularis（2-4 年）。 A 组织中的高增殖率（10% 细胞核分裂）和细胞凋亡。鳃盖符合扇贝的高能量吞吐量和减少对抗氧化防御机制的投资。相反，A 中的细胞更新缓慢（<1% 细胞核分裂）。年轻和年老个体的外套膜、鳃和内收肌相似。在心脏中，细胞更新率随着年龄的增长而降低，这表明衰老过程中受损细胞的清除效率较低。岛屿。德国湾斑驴和冰岛斑驴的细胞更新率、质量比呼吸和抗氧化酶活性相似。地理位置不同的人的最大预期寿命不同 A.岛屿种群是由外在因素决定的，而不是由基本的生理差异决定的。
Cell proliferation and apoptosis were investigated in tissues of two bivalve species,Arctica islandicafrom the German Bight (age of bivalves: 33–98 years) and Iceland (7–148 years) andAequipecten opercularisfrom the English Channel (2–4 years). High proliferation rates (10% nuclei dividing) and apoptosis in tissues ofA. operculariswere in line with high-energy throughput and reduced investment into antioxidant defence mechanisms in the scallop. In contrast, cell turnover was slow (<1% nuclei dividing) inA. islandicaand similar in mantle, gill and adductor muscle between young and old individuals. In the heart, cell turnover rates decreased with age, which indicates less-efficient removal of damaged cells in ageingA. islandica. Cell turnover rates, mass specific respiration and antioxidant enzyme activities were similar in German Bight and Iceland ocean quahog. Variable maximum life expectancies in geographically separatedA. islandicapopulations are determined by extrinsic factors rather than by fundamental physiological differences.