Real-time handheld multispectral optoacoustic imaging
Real-time handheld multispectral optoacoustic imaging
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DOI：
10.1364/ol.38.001404
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发表时间：
2013-05-01
期刊：
影响因子：
3.6
通讯作者：
Ntziachristos, Vasilis
中科院分区：
文献类型：
--
作者：
Buehler, Andreas;Kacprowicz, Marcin;Ntziachristos, Vasilis
多光谱光声断层扫描（MSOT）的功能和分子对比有可能在临床实践中找到广泛的部署。我们已经开发出第一个手持MSOT成像设备与快速波长调谐实现50赫兹的帧速率。在这封信中，我们通过在人类志愿者中动态解析多种疾病相关组织发色团（包括氧合/脱氧血红蛋白和黑色素）来证明其临床潜力。(C)2013年美国光学学会
Multispectral optoacoustic tomography (MSOT) of functional and molecular contrast has the potential to find broad deployment in clinical practice. We have developed the first handheld MSOT imaging device with fast wavelength tuning achieving a frame rate of 50 Hz. In this Letter, we demonstrate its clinical potential by dynamically resolving multiple disease-relevant tissue chromophores, including oxy-/deoxyhemoglobin, and melanin, in human volunteers. (C) 2013 Optical Society of America