Neurocognitive functioning in adolescents with eating disorders: A population-based study
Neurocognitive functioning in adolescents with eating disorders: A population-based study
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DOI：
10.1080/13546805.2012.698592
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发表时间：
2013-09-01
影响因子：
1.7
通讯作者：
Foster, Jonathan K.
中科院分区：
文献类型：
--
作者：
Allen, Karina L.;Byrne, Susan M.;Foster, Jonathan K.
导言。神经认知缺陷已经在饮食障碍中被发现，包括神经性厌食症和神经性暴食症。然而，目前的数据不能就这些赤字的性质或程度得出明确的结论。目前的研究旨在评估患有和不患有进食障碍的青少年的神经认知功能。受试者(N=669)来自西澳大利亚妊娠队列(RAINE)研究。认知测试是使用计算机化的CogState评估电池进行的。饮食障碍症状使用改编自儿童饮食障碍检查和饮食障碍检查问卷的问题进行评估。将符合全部或部分DSM-IV饮食障碍标准的青少年(n=58)与没有明显饮食病理的青少年(n=592)进行比较。进食障碍样本在包括全局处理和定势转移在内的执行功能指标上表现出受损，但在视觉注意力和警觉性指标上的表现好于对照组参与者。这是第一项以人群为基础的饮食障碍青少年样本评估神经认知功能的研究。在进食障碍的早期，为中枢连贯性弱和定势转移困难提供了支持。需要研究来确定这些缺陷是否先于并预测进食障碍的发生。
Introduction. Neurocognitive deficits have been identified in eating disorders, including anorexia nervosa and bulimia nervosa. However, current data do not allow for firm conclusions regarding the nature or extent of these deficits. The current study aimed to evaluate neurocognitive functioning in a population-based sample of adolescents with and without eating disorders.Methods. Participants (N = 669) were drawn from the Western Australian Pregnancy Cohort (Raine) Study. Cognitive testing was conducted using the computerised CogState assessment battery. Eating disorder symptoms were assessed using questions adapted from the Child Eating Disorder Examination and Eating Disorder Examination-Questionnaire. Adolescents who met full or partial criteria for a DSM-IV eating disorder (n = 58) were compared to adolescents with no significant eating pathology (n = 592).Results. The eating disorder sample showed impaired performance on measures of executive functioning, including global processing and set shifting, but performed better than control participants on measures of visual attention and vigilance.Conclusions. This is the first study to evaluate neurocognitive functioning in a population-based sample of adolescents with eating disorders. Support is provided for weak central coherence and set-shifting difficulties early in the course of eating disorders. Research is needed to determine if these deficits precede and predict eating disorder onset.