Testicular Cancer Epidemiology, Diagnosis, and Management

Testicular Cancer Epidemiology, Diagnosis, and Management
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DOI:
10.1016/j.mcna.2017.10.003
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发表时间:
2018-03-01
影响因子:
5.9
通讯作者:
Eggener, Scott E.
Eggener, Scott E.
中科院分区:
医学2区
文献类型:
--
作者:
Smith, Zachary L.;Werntz, Ryan P.;Eggener, Scott E.

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据估计,2016年美国有8720例睾丸癌(TC)新发病例。这种疾病的原因很复杂,有几个环境和遗传风险因素。虽然这种疾病很罕见,但发病率一直在稳步上升。幸运的是,在过去的几十年里,治疗取得了重大进展,使TC成为最可治愈的恶性肿瘤之一。然而,由于TC通常发生在年轻男性中,因此考虑治疗对生育力,生活质量和长期毒性的影响至关重要;必须根据患者的临床和病理结果对患者采取个性化方法。
There were an estimated 8720 new cases of testicular cancer (TC) in the United States in 2016. The cause of the disease is complex, with several environmental and genetic risk factors. Although the disease is rare, the incidence has been steadily increasing. Fortunately, substantial advances in treatment have occurred over the last few decades, making TC one of the most curable malignancies. However, because TC typically occurs in younger men, considerations of the treatment impact on fertility, quality of life, and long-term toxicity are paramount; an individualized approach must be taken with patients based on their clinical and pathologic findings.