Magnetic resonance identification of the ventricular tachycardia critical isthmus: finding the needle in the haystack.

Magnetic resonance identification of the ventricular tachycardia critical isthmus: finding the needle in the haystack.
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室性心动过速临界峡部的磁共振识别:大海捞针。

DOI:
10.1016/j.jacc.2010.07.042
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发表时间:
2011
影响因子:
24
通讯作者:
Nazarian,Saman
Nazarian,Saman
中科院分区:
医学1区
文献类型:
--
作者:
Halperin,HenryR;Nazarian,Saman

文献摘要

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恶性室性心律失常的导管治疗已取得了重大进展。值得注意的最初里程碑包括Hecht的第一次心内记录(1),以及Furman和罗宾逊的基于导管的心脏刺激演示(2)。后来,Wellens et al. (3)证明程序电刺激可以可靠地启动和终止易感个体的室性心动过速(VT)回路。这些工具使电生理学家能够更好地理解室性心动过速的机制、关键通路和起源部位,以及潜在的新疗法。
Significant strides have been made in development of catheter-based therapeutics for cure of malignant ventricular arrhythmias. Notable initial milestones included the first intracardiac recordings made by Hecht (1), and demonstration of catheter-based cardiac stimulation by Furman and Robinson (2). Later, Wellens et al.(3) demonstrated that programmed electrical stimulation could reliably initiate and terminate ventricular tachycardia (VT) circuits in susceptible individuals. These tools allowed electrophysiologists to grow in their understanding of VT mechanisms, critical pathway, and sites of origin, and potential new therapeutics.