SAPALDIA: Methods and participation in the cross-sectional part of the Swiss study on air pollution and lung diseases in adults
SAPALDIA: Methods and participation in the cross-sectional part of the Swiss study on air pollution and lung diseases in adults
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DOI：
10.1007/bf01318136
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发表时间：
1997-01-01
期刊：
影响因子：
--
通讯作者：
Villiger, B
中科院分区：
文献类型：
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作者：
Martin, BW;AckermannLiebrich, U;Villiger, B
SAPALDIA -瑞士关于空气污染和成人肺部疾病的研究-专注于低至中等水平的空气污染物对健康的长期影响，这是瑞士不同地区的典型情况。1997年进行的SAPALDIA横断面研究的目的是确定支气管哮喘、慢性支气管炎和过敏性疾病在瑞士成年人口中的流行率，并确定潜在影响因素的重要性。这些可能是个人的（吸烟习惯，过敏状况，家族史职业）和环境（室外和室内污染，空气过敏原，气候）。横断面研究的另一个目的是确定在两年观察期内易出现症状的个体，并将其纳入SAPALDIA随访研究。本技术报告是SAPALDIA横断面研究的方法学文件。仪器和标准化的方法进行了介绍和讨论。医学检查包括使用标准化问卷进行的计算机化访谈、采集用于血清学试验的血液样本、过敏皮肤试验、呼气末CO和身高测量以及肺功能试验，随后进行乙酰甲胆碱激发试验或支气管扩张试验。的参与模式和9651名参与者的研究，代表59.3%的样本，进行了说明。基于非参与者通过电话采访和邮寄的简短问卷获得的信息，可能的选择偏差进行了量化和讨论。
SAPALDIA - the Swiss Study on Air Pollution and Lung Diseases in Adults-focuses on the long term health effects of low to moderate levels of air pollutants as typically seen in different parts of Switzerland. The aim of the SAPALDIA cross-sectional study carried out in 1997 was to determine the prevalence of bronchial asthma, chronic bronchitis and allergic conditions in the adult population of Switzerland and to identify and to determine the respective importance of potentially influencing factors. These could be both personal (smoking habits, allergy status, family history occupation) and environmental (outdoor and indoor pollution, aeroallergens, climate). A further aim of the cross-sectional study consisted in the identification of individuals susceptible to present symptoms during a two year observation period and to be included in the SAPALDIA follow-up study. This technical report represents the methodological documentation for the cross-sectional study of SAPALDIA. The instruments and the methods of standardisation are presented and discussed. The medical examination consisted of a computerised interview using a standardised questionnaire, the taking of a blood sample for serological tests, allergy skin testing the measurement of endexpiratory CO and body height, and pulmonary function testing followed by methacholine challenge testing or bronchodilatation testing. The pattern of participation and the 9651 participants of the study representing 59.3 % of the sample, are described. Based on information on non-participants gained by telephone interviews and mailed short questionaires, possible selection biases are quantified and discussed.