Bayesian approach to longitudinal craniofacial growth: The Craniofacial Growth Consortium Study.
Bayesian approach to longitudinal craniofacial growth: The Craniofacial Growth Consortium Study.
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DOI：
10.1002/ar.24520
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发表时间：
2021-05
期刊：
影响因子：
--
通讯作者：
Middleton KM
中科院分区：
文献类型：
--
作者：
Sherwood RJ;Oh HS;Valiathan M;McNulty KP;Duren DL;Knigge RP;Hardin AM;Holzhauser CL;Middleton KM
20 世纪初，北美各地发起了一系列研究来调查和描述儿童成长的特征。颅面生长联盟研究 (CGCS) 结合了其中六项生长研究的颅面记录（来自 1,913 人的 15,407 幅侧位头颅照片；其中 956 名女性，957 名男性，主要是欧洲血统）。从 CGCS 的六项研究中收集的标准头影测量点可以直接比较北美六个地点的颅面生长模式。三名评估员收集了所有头影测量点，并对每个点的坐标进行平均。根据平均坐标计算出十二个测量值。我们实施了一个多级双逻辑方程来估计按性别分别拟合每个特征的生长轨迹。使用贝叶斯推理，我们为具有不同随机效应结构的每个性状拟合三个模型，以比较研究之间生长模式的差异。该模型成功地识别了大多数性状的重要生长里程碑（例如，达到峰值生长速度的年龄、停止生长的年龄）。在少数情况下，由于某些研究的年龄范围被截断以及某些测量的缓慢而稳定的增长，这些里程碑无法确定。结果表明，关于颅面生长里程碑估计和生长曲线整体形状的六项生长研究之间非常相似。这些相似之处表明，由于方案、样本或可能的地理差异的差异，研究之间存在微小差异。分析表明，支持将这些研究合并到 CGCS 中，而无需担心存在偏倚。因此，CGCS 提供了一个无与伦比的机会来检查从儿童到成年的颅面生长情况。
Early in the 20th century, a series of studies were initiated across North America to investigate and characterize childhood growth. The Craniofacial Growth Consortium Study (CGCS) combines craniofacial records from six of those growth studies (15,407 lateral cephalograms from 1,913 individuals; 956 females, 957 males, primarily European descent). Standard cephalometric points collected from the six studies in the CGCS allows direct comparison of craniofacial growth patterns across six North American locations. Three assessors collected all cephalometric points and the coordinates were averaged for each point. Twelve measures were calculated from the averaged coordinates. We implemented a multilevel double logistic equation to estimate growth trajectories fitting each trait separately by sex. Using Bayesian inference, we fit three models for each trait with different random effects structures to compare differences in growth patterns among studies. The models successfully identified important growth milestones (e.g., age at peak growth velocity, age at cessation of growth) for most traits. In a small number of cases, these milestones could not be determined due to truncated age ranges for some studies and slow, steady growth in some measurements. Results demonstrate great similarity among the six growth studies regarding craniofacial growth milestone estimates and the overall shape of the growth curve. These similarities suggest minor variation among studies resulting from differences in protocol, sample, or possible geographic variation. The analyses presented support combining the studies into the CGCS without substantial concerns of bias. The CGCS, therefore, provides an unparalleled opportunity to examine craniofacial growth from childhood into adulthood.
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DOI：
10.1016/0002-9416(72)90026-7
发表时间：
1972-01-01
期刊：
AMERICAN JOURNAL OF ORTHODONTICS
影响因子：
--
作者：
BUCK, DL;CHURCH, DH
通讯作者：
CHURCH, DH
影响因子：
1.7
作者：
ELLOZY, M
通讯作者：
ELLOZY, M
影响因子：
2.8
作者：
Duren, Dana L.;Seselj, Maja;Sherwood, Richard J.
通讯作者：
Sherwood, Richard J.
影响因子：
5.8
作者：
Carpenter, Bob;Gelman, Andrew;Riddell, Allen
通讯作者：
Riddell, Allen
影响因子：
4.1
作者：
Duren, Dana L.;Blangero, John;Towne, Bradford
通讯作者：
Towne, Bradford